Using ventilation-induced aortic pressure and flow variation to diagnose preload responsiveness

  • Michael R. Pinsky

Abstract

The recent literature has documented that both arterial pulse pressure [1] and left ventricular stroke volume variations [2] induced by positive-pressure ventilation are sensitive and specific markers of preload responsiveness. The greater the degree of flow or pressure variation over the course of the respiratory cycle for a fixed tidal volume, the more likely the subject is to increase their cardiac output in response to a volume challenge and the greater that increase may be. Slama et al. [3] report in this issue that in a rabbit model of graded hemorrhage measuresof aortic flow variation during positive-pressureventilation cardiac output will increase in response to volume expansion. Furthermore

Keywords

Pulse Pressure Variation Stroke Volume Variation Aortic Flow Pulmonary Artery Occlusion Pressure Arterial Pulse Pressure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Michael R. Pinsky
    • 1
  1. 1.Department of Intensive Care MedicineUniversity of Pittsburgh Medical CenterPittsburghUSA

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