Using ventilation-induced aortic pressure and flow variation to diagnose preload responsiveness
The recent literature has documented that both arterial pulse pressure  and left ventricular stroke volume variations  induced by positive-pressure ventilation are sensitive and specific markers of preload responsiveness. The greater the degree of flow or pressure variation over the course of the respiratory cycle for a fixed tidal volume, the more likely the subject is to increase their cardiac output in response to a volume challenge and the greater that increase may be. Slama et al.  report in this issue that in a rabbit model of graded hemorrhage measuresof aortic flow variation during positive-pressureventilation cardiac output will increase in response to volume expansion. Furthermore
KeywordsPulse Pressure Variation Stroke Volume Variation Aortic Flow Pulmonary Artery Occlusion Pressure Arterial Pulse Pressure
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