Bayesian Methods in SAXS and SANS Structure Determination
Small-angle scattering (SAS) is an experimental technique which may be used to derive size and shape information about large molecules in solution (e.g. [228, 177]). Also molecular interaction and aggregation behavior may be studied by small-angle scattering. Solution scattering experiments using X-rays (SAXS) were initiated in the 1950s and scattering experiments using neutrons (SANS) followed about a decade later. Static light scattering (SLS) which probes larger sizes than SAXS and SANS is frequently used as a complementary technique e.g. for detection of aggregation.