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The Spiral Peripheral Nerve Interface: Design, Fabrication and Performance

  • Edward J Tarte
  • James J. FitzGerald
  • Natalia Lago
  • Samia Benmerah
  • Jordi Serra
  • Christopher P. Watling
  • Ruth E. Cameron
  • Stéphanie P. Lacour
  • Stephen B. McMahon
  • James W. Fawcett
Conference paper
  • 188 Downloads
Part of the IFMBE Proceedings book series (IFMBE, volume 37)

Abstract

We have developed a novel peripheral nerve interface device based on photosensitive polyimides in which nerve fibres regenerate through channels containing electrodes. These Spiral Peripheral Nerve Interfaces (SPNIs) are fabricated by spin coating and curing a layer of polyimide resin onto a silcon handle wafer. Channels 100μm wide are defined in a 100..m thick photosensitive polyimide (PSPI) layer photolithographically. Metal wiring is integrated between the two and encapsulated using a thinner PSPI layer. This design has advantages over others in terms of both recording and stimulation. Initial tests of the device carried out in-vivo show successful regeneration and have demonstrated that we can record signals from regenerated axons.

Keywords

Neural interface prosthesis peripheral nerve 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Edward J Tarte
    • 1
  • James J. FitzGerald
    • 2
  • Natalia Lago
    • 3
  • Samia Benmerah
    • 1
  • Jordi Serra
    • 3
  • Christopher P. Watling
    • 4
  • Ruth E. Cameron
    • 4
  • Stéphanie P. Lacour
    • 5
  • Stephen B. McMahon
    • 3
  • James W. Fawcett
    • 2
  1. 1.School of Electronic, Electrical and Computer engineeringUniversity of BirminghamBirminghamUK
  2. 2.Centre for Brain RepairUniversity of CambridgeCambridgeUK
  3. 3.Neurorestoration group, King’s College LondonLondonUK
  4. 4.Department of Materials Science and MetallurgyUniversity of CambridgeCambridgeUK
  5. 5.Institute of MicroengineeringEPFLLausanneSwitzerland

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