Evaluation of Assam Bora Rice as a Natural Mucoadhesive Matrixing Agent for Controlled Drug Delivery

  • Nikhil K. Sachan
  • S. Pushkar
  • S. K. Ghosh

Abstract

The Present study envisages pharmaceutical utility of Assam Bora rice as biopolymeric excipient in drug delivery. The sustained release potential from the proposed matrix backbone was investigated through in vitro dissolution studies of microbeads prepared by an industrially feasible conventional ionotropic gelation method using the blends of pregelatinized Bora rice along with sodium alginate, as per SUPAC-MR guidelines. The prepared beads were characterized for surface morphology, drug-polymer compatibility, mucoadhesion and other pharmacotechnical parameters. The outcomes of studies have demonstrated that Assam Bora rice holds the promise of being used as a drug release modulator in the drug carrier systems.

Keywords

Drug Release Sodium Alginate Entrapment Efficiency Mucoadhesive Property Glutinous Rice 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Nikhil K. Sachan
    • 1
  • S. Pushkar
    • 1
  • S. K. Ghosh
    • 2
  1. 1.University Institute of PharmacyC. S. J. M. UniversityKanpurIndia
  2. 2.Department of Pharmaceutical SciencesDibrugarh UniversityDibrugarhIndia

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