AIME 2011: Artificial Intelligence in Medicine pp 296-301 | Cite as
A Constraint Logic Programming Approach to Identifying Inconsistencies in Clinical Practice Guidelines for Patients with Comorbidity
Abstract
This paper describes a novel methodological approach to identifying inconsistencies when concurrently using multiple clinical practice guidelines. We discuss how to construct a formal guideline model using Constraint Logic Programming, chosen for its ability to handle relationships between patient information, diagnoses, and treatment suggestions. We present methods to identify inconsistencies that are manifested by treatment-treatment and treatment-disease interactions associated with comorbidity. Using an open source constraint programming system (ECLiPSe), we demonstrate the ability of our approach to find treatment given incomplete patient data and to identify possible inconsistencies.
Keywords
Clinical practice guideline comorbidity Constraint Logic ProgrammingPreview
Unable to display preview. Download preview PDF.
References
- 1.Dechter, R.: Constraint Processing. The MIT Press, Cambridge (1989)MATHGoogle Scholar
- 2.Cabana, M.D., Rand, C.S., Powe, N.R., Wu, A.W., Wilson, M.H., Abboud, P.A.C., Rubin, H.R.: Why don’t physicians follow clinical practice guidelines? a framework for improvement. Journ. of the American Medical Assoc. 282, 1458–1465 (1999)CrossRefGoogle Scholar
- 3.Latoszek-Berendsen, A., Tange, H., van den Herik, J., Hasman, A.: From clinical practice guidelines to computer-interpretable guidelines. Methods of Information in Medicine 49(6), 550–570 (2010)CrossRefGoogle Scholar
- 4.Horvitz, E.: Automated reasoning for biology and medicine. In: Advances in Computer Methods for Systematic Biology: Artificial Intelligence, Databases, and Computer Vision (1993)Google Scholar
- 5.Charles, J., Petrie, J.: Revised dependency-directed backtracking for default reasoning’. In: AAAI 1987, pp. 167–172 (1987)Google Scholar
- 6.Hing, M.M., Michalowski, M., Wilk, S., Michalowski, W., Farion, K.: Identifying inconsistencies in multiple clinical practice guidelines for a patient with co-morbidity. In: Proc. of KEDDH 2010, pp. 447–452 (2010)Google Scholar
- 7.Lindblad, C., Hanlon, J., Ross, C., Sloane, R., Pieper, C., Hajjar, E., Ruby, C., Schmader, K.: Clinically important drug-disease interactions and their prevalence in older adults. Clinical Therapeutics 28(8), 1133–1143 (2006)CrossRefGoogle Scholar