Pixel Mask Analyzer (PMA): Noise Removal in Gland Detection for Colon Cancer Image

  • Mohd Yamin Ahmad
  • Yasmin Anum Mohd Yusof
  • Siti Aishah Md. Ali
  • Azlinah Mohamed
Part of the Communications in Computer and Information Science book series (CCIS, volume 179)

Abstract

It is well known that for any type of cancer, mortality rate can be reduced by early detection of the cancer. Detection of cancer markers from the time of taking blood from patients until microscopic examination of the biopsy tissues is not only laborious but time consuming. It is known that with the help of a computerized system, the diagnosis time can be shortened. In this paper, we proposed the method of gland edge detection and noise removal using Pixel Mask Analyzer (PMA) as image enhancement. PMA is based on kFill filter that uses 5x5 mask slide through entire 2D biopsies tissue images. Pixels within mask are analyzed on 8 sample images to remove noise. We compare the median filter and PMA and found that PMA gives better result on noise removal. After noise removal, Sobel and Canny edge detectors are applied on the images and we found that Canny provides better output for edge detection. The output of this detection is important for further analysis of colon cancer cells image detection.

Keywords

Colorectal Cancer Gland Detection Adenocarcinoma Image Processing Noise Removal Pattern Recognition Computer Aided Diagnosis 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Kerr, D.J., Young, M.A., Richard Hobbs, F.D.: ABC of colorectal cancer, pp. 1–15 (2001)Google Scholar
  2. 2.
    Meyerhardt, J., Saunders, M.: In: Skarin, A.T. (ed.) Colorectal Cancer, pp. 23–53 (2007)Google Scholar
  3. 3.
    Tan, C.L., Cao, R., Wang, Q., Shen, P.: Character extraction from interfering background - analysis of double-sided handwritten archival documents. In: Singh, S., Murshed, N., Kropatsch, W.G. (eds.) ICAPR 2001. LNCS, vol. 2013, p. 93. Springer, Heidelberg (2001)CrossRefGoogle Scholar
  4. 4.
    Mohd Rahim, M.S., Nik Ismail, N.I., Shah Idris, M.A.: The Use of Hybrid Technique: Thresholding And Edge Detection For Identifying River From Aerial Photo. Journal Teknology 41(B) (2004)Google Scholar
  5. 5.
    Al-Khaffaf, H.S.M., Talib, A.Z., Salam, R.A.: Removing salt-and-pepper noise from binary images of engineering drawings. In: 19th International Conference on Pattern Recognition, Tampa, Florida, USA, vol. 1(6), pp. 1271–1274 (2008)Google Scholar
  6. 6.
    Chinnasarn, K., Rangsanseri, Y., Thitimajshima, P.: Removing salt-and-pepper noise in text/graphics images. In: The 1998 IEEE Asia-Pacific Conference on Circuits and Systems, Chiangmai, pp. 459–462 (1998)Google Scholar
  7. 7.
    Jamil, N., Sembok, T.M.T.: Gradient-based edge detection of songket motifs. In: Sembok, T.M.T., Zaman, H.B., Chen, H., Urs, S.R., Myaeng, S.-H. (eds.) ICADL 2003. LNCS, vol. 2911, pp. 456–467. Springer, Heidelberg (2003)CrossRefGoogle Scholar
  8. 8.
    Hern´andez-Cisneros, R.R., Terashima-Mar´ın, H.: Detection and Classification of Microcalcification Clusters in Mammograms Using Evolutionary Neural Networks, pp. 151–175 (2009)Google Scholar
  9. 9.
    Pathology Outline Website, http://www.pathologyoutlines.com/colontumor.html (visited at January 20, 2011)
  10. 10.
    Mathworks Inc.: Image Processing ToolboxTM 6 User’s Guide, pp. 17- 246 (2008)Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Mohd Yamin Ahmad
    • 1
  • Yasmin Anum Mohd Yusof
    • 2
  • Siti Aishah Md. Ali
    • 3
  • Azlinah Mohamed
    • 1
  1. 1.Faculty of Computer and Mathematical SciencesUniversity Technology MARAShah AlamMalaysia
  2. 2.Department of Biochemistry, Faculty of MedicineUniversiti Kebangsaan MalaysiaKuala LumpurMalaysia
  3. 3.Department of PathologyUKM Medical CentreKuala LumpurMalaysia

Personalised recommendations