Positively versus Negatively Frequency-Dependent Selection

  • Robert Morris
  • Tim Watson
Part of the Lecture Notes in Computer Science book series (LNCS, volume 5778)


Frequency-dependent selection (FDS) refers to situations where individual fitnesses are dependent (to some degree) on where the individual’s alleles lie in the proximate allele frequency distribution. If the dependence is negative – that is, if alleles become increasingly detrimental to fitness as they become increasingly common at a given locus – then genetic diversity may be maintained. If the dependence is positive, then alleles may converge at given loci.

A hypothetical evolutionary model of FDS is here presented, in which the individuals themselves determined – by means of a gene – whether their fitnesses were positively or negatively frequency-dependent. The population ratio of the two types of individual was monitored in runs with different parameters, and explanations of what happened are offered.


Frequency-dependent selection multiple alleles meta gene 


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  1. 1.
    Asmussen, M.A., Basnayake, E.: Frequency-Dependent Selection: The High Potential for Permanent Genetic Variation in the Diallelic, Pairwise Interaction Model. Genetics 125, 215–230 (1990)Google Scholar
  2. 2.
    Bürger, R.: A Multilocus Analysis of Intraspecific Competition and Stabilizing Selection on a Quantitative Trait. Journal of Math. Biology 50, 355–396 (2005)MathSciNetCrossRefzbMATHGoogle Scholar
  3. 3.
    Curtsinger, J.W.: Evolutionary Principles for Polynomial Models of Frequency-Dependent Selection. Proc. Natl. Acad. Sci. USA 81, 2840–2842 (1984)CrossRefzbMATHGoogle Scholar
  4. 4.
    Grefenstette, J.J.: Evolvability in Dynamic Fitness Landscapes: A Genetic Algorithm Approach. In: Proc. of the 1999 Conf. on Ev. Comp., pp. 2031–2038 (1999)Google Scholar
  5. 5.
    Hillman, J.P.A., Hinde, C.J.: Evolving UAV Tactics with an Infected Genome. In: Proc. of the 5th UK Workshop on Comp. Intel., pp. 243–250 (2005)Google Scholar
  6. 6.
  7. 7.
    Roff, D.A.: The Maintenance of Phenotypic and Genetic Variation in Threshold Traits by Frequency-Dependent Selection. Journal of Evolutionary Biology 11, 513–529 (1998)CrossRefGoogle Scholar
  8. 8.
    Schneider, K.A.: A Multilocus-Multiallele Analysis of Frequency- Dependent Selection Induced by Intraspecific Competition. Journal of Math. Biology 52, 483–523 (2006)MathSciNetCrossRefzbMATHGoogle Scholar
  9. 9.
    Trotter, M.V., Spencer, H.G.: Frequency-Dependent Selection and the Maintenance of Genetic Variation: Exploring the Parameter Space of the Multiallelic Pairwise Interaction Model. Genetics 176, 1729–1740 (2007)CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Robert Morris
    • 1
  • Tim Watson
    • 1
  1. 1.Faculty of TechnologyDe Montfort UniversityLeicesterUnited Kingdom

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