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Goal-directed Coagulation Management in Major Trauma

  • H. Schoechl
  • W. Voelckel
  • C. Solomon
Chapter
  • 1.7k Downloads
Part of the Annual Update in Intensive Care and Emergency Medicine 2011 book series (AUICEM, volume 1)

Abstract

Severe tissue trauma is frequently associated with hemorrhagic shock and subsequent pronounced coagulopathy [1]. Uncontrolled bleeding is the second most common cause of death, and hemorrhage is directly responsible for 40 % of all trauma-related deaths [2]. Coagulopathy can be detected with standard coagulation tests immediately after arrival in the emergency room (ER) in approximately 25–35 % of all trauma patients [1], [2]. Moreover, early trauma-induced coagulopathy is associated with a 4-fold increase in mortality [1]. Blood coagulation monitoring is essential in order to assess the underlying coagulation disorder and to tailor hemostatic treatment. Thromboelastometry (TEM) and thrombelastography (TEG) are promising point-of-care technologies providing rapid information on the initiation process of clot formation, clot quality, and stability of the clot [3].

Keywords

Trauma Patient Fresh Freeze Plasma Thrombin Generation Major Trauma Massive Transfusion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media LLC 2011

Authors and Affiliations

  • H. Schoechl
    • 1
  • W. Voelckel
    • 2
  • C. Solomon
    • 3
  1. 1.Ludwig Boltzmann Institute of Experimental and Clinical TraumatologyAUVA Trauma Research CenterViennaAustria
  2. 2.Department of Anesthesiology and Intensive Care MedicineAUVA Trauma CenterSalzburgAustria
  3. 3.Department of Anesthesiology, Intensive Care and Perioperative MedicineUniversity HospitalSalzburgAustria

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