Epigenetics and Human Reproduction pp 279-288
Nuclear Lamins in Mammalian Spermatogenesis
Nuclear lamins are important structural protein components of the nuclear envelope. The composition and properties of the nuclear lamina of spermatogenic cells differ significantly from those of somatic cells of the same species. Mammalian spermatogenic cells selectively express short lamin isoforms showing several peculiarities. In this chapter, we summarize what is known about germ line-specific lamins and discuss their possible relevance for germ cell differentiation and fertility.