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Reducing Artifacts in TMS-Evoked EEG

  • Juan José Fuertes
  • Carlos M. Travieso
  • A. Álvarez
  • M. A. Ferrer
  • J. B. Alonso
Part of the Lecture Notes in Computer Science book series (LNCS, volume 6076)

Abstract

Transcranial magnetic stimulation induces weak currents within the cranium to activate neuronal firing and its response is recorded using electroencephalography in order to study the brain directly. However, different artifacts contaminate the results. The goal of this study is to process these artifacts and reduce them digitally. Electromagnetic, blink and auditory artifacts are considered, and Signal-Space Projection, Independent Component Analysis and Wiener Filtering methods are used to reduce them. These last two produce a successful solution for electromagnetic artifacts. Regarding the other artifacts, processed with Signal-Space Projection, the method reduces the artifact but modifies the signal as well. Nonetheless, they are modified in an exactly known way and the vector used for the projection is conserved to be taken into account when analyzing the resulting signals. A system which combines the proposed methods would improve the quality of the information presented to physicians.

Keywords

Transcranial magnetic stimulation electroencephalogram artifact electromagnetic blink auditory 

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References

  1. 1.
    Barker, A.T., Jalinous, R., Freeston, I.L.: Non-invasive magnetic stimulation of human motor cortex. Lancet 1, 1106–1107 (1985)CrossRefGoogle Scholar
  2. 2.
    Ilmoniemi, R.J.: Transcranial magnetic stimulation. Wiley Encyclopedia of Biomedical Engineering (2006)Google Scholar
  3. 3.
    Komssi, S., Savolainen, P., Heiskala, J., Kähkönen, S.: Excitation threshold of the motor cortex estimated with transcranial magnetic stimulation electroencephalography. NeuroReport 18(1), 13–16 (2007)CrossRefGoogle Scholar
  4. 4.
    Nikulin, V.V., Kicic, D., Kähkönen, S., Ilmoniemi, R.J.: Modulation of electroencephalographic responses to transcranial magnetic stimulation: evidence for changes in cortical excitability related to movements. European Journal of Neuroscience 18(5), 1206–1212 (2003)CrossRefGoogle Scholar
  5. 5.
    Uusitalo, M.A., Ilmoniemi, R.J.: Signal-space projection method for separating MEG or EEG into components. Med. & Biol. Eng. & Comput. 35(2), 135–140 (1997)CrossRefGoogle Scholar
  6. 6.
    Hyvärinen, A., Oja, E.: Independent component analysis: algorithms and applications. Neuronal Networks 13(4-5), 411–430 (2000)CrossRefGoogle Scholar
  7. 7.
    Zhukov, L., Weinstein, D., Johnson, C.: Independent component analysis for EEG source localization. IEEE Engineering in Medicine and Biology 19(3), 87–96 (2000)CrossRefGoogle Scholar
  8. 8.
    Vigário, R., Särelä, J., Jousmäki, V., Hämäläinen, M., Oja, E.: Independent component approach to the analysis of EEG and MEG recordings. IEEE Transactions on Biomedical Engineering 47(5), 589–593 (2000)CrossRefGoogle Scholar
  9. 9.
    Ferrer Ballester, M.A., Travieso González, C.M., Alonso Hernández, J.B.: Tratamiento digital de la señal: fundamentos y aplicaciones. ULPGC Editions (June 27, 2005)Google Scholar
  10. 10.
    Haykin, S.: Adaptive filter theory. Prentice-Hall, Inc., Upper Saddle River (1986)zbMATHGoogle Scholar
  11. 11.
    Ilmoniemi, R.J., Karhu, J.: TMS and EEG: Methods and current advancements. In: Oxford handbook of Transcranial stimulation, February 2008. Oxford University Press, Oxford (2008)Google Scholar
  12. 12.
    Nikouline, V., Ruohonen, J., Ilmoniemi, R.J.: The role of the coil click in TMS assessed with simultaneous EEG. Clinical Neurophysiology 110(8), 1325–1328 (1999)CrossRefGoogle Scholar
  13. 13.
    Huotilainen, M., Ilmoniemi, R.J., Tiitinen, H., Lavikainen, J., Alho, K., Kajola, M., Näätänen, R.: The projection method in removing eye-blink artifacts from multichannel MEG measurements. In: Biomagnetism: Fundamental Research and Clinical Applications. Elsevier Science, IOS Press (1995)Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Juan José Fuertes
    • 1
  • Carlos M. Travieso
    • 2
  • A. Álvarez
    • 2
  • M. A. Ferrer
    • 2
  • J. B. Alonso
    • 2
  1. 1.Instituto Interuniversitario de Investigación en Bioingeniería y Tecnología Orientada al Ser, HumanoUniversidad Politécnica de ValenciaValenciaEspaña
  2. 2.Dpto. de Señales y ComunicacionesUniversidad de Las Palmas de Gran Canaria, Centro Tecnológico para la Innovación en ComunicacionesLas Palmas de Gran CanariaEspaña

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