Oncology and Kidney

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First Online:

Abstract

The pediatric nephrologist may at times be asked to evaluate renal dysfunction in a patient with cancer. This chapter gives an overview of various such scenarios. The section on renal tumors delineates common presentations, patient evaluation, and therapy plans in common pediatric kidney tumors. The section on “nephrology consults in oncology” deals with tumor lysis syndrome, chemotherapy-induced renal dysfunction, and secondary hypertension. These clinical scenarios require understanding and cooperation from both the nephrologist and the oncologist to optimize therapy. The last section deals with stem cell transplantation and renal issues arising in this setting. A short overview regarding the procedure is followed by a summary of renal concerns during and following a stem cell transplant.

Keywords

Stem Cell Transplantation Acute Kidney Injury Renal Tumor Graft Versus Host Disease Thrombotic Thrombocytopenic Purpura 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Suggested Reading

  1. Ali Varan (2008) Wilms’ tumor in children: an Overview. Nephron Clin Pract 108:c83–c90. doi: 10-1159/000113012 PubMedCrossRefGoogle Scholar
  2. Cairo MS, Coiffier B, Reiter A, Younes A, TLS Expert Panel (2010) Recommendations for the evaluation of risk and prophylaxis of tumor lysis syndrome (TLS) in adults and children with malignant diseases: an expert TLS panel consensus. Br J Haematol 149(4):578–586PubMedCrossRefGoogle Scholar
  3. Coiffier B, Altman A, Pui CH, Younes A, Cairo MS (2008) Guidelines for the management of pediatric and adult tumor lysis syndrome: an evidence-based review. J Clin Oncol 26(16):2767–2778PubMedCrossRefGoogle Scholar
  4. Ellis MJ, Parikh CR, Inrig JK, Kanbay M, Patel UD (2008) Chronic kidney disease after hematopoietic cell transplantation: a systematic review. Am J Transplant 8(11):2378–2390PubMedCentralPubMedCrossRefGoogle Scholar
  5. Kersting S, Koomans HA, Hené RJ, Verdonck LF (2007) Acute renal failure after allogeneic myeloablative stem cell transplantation: retrospective analysis of incidence, risk factors and survival. Bone Marrow Transplant 39(6):359–365PubMedCrossRefGoogle Scholar
  6. Lam AQ, Humphreys BD (2012) Onco-nephrology: AKI in the cancer patient. Clin J Am Soc Nephrol 7(10):1692–1700PubMedCentralPubMedCrossRefGoogle Scholar
  7. Perazella MA (2012) Onco-nephrology: renal toxicities of chemotherapeutic agents. Clin J Am Soc Nephrol 7(10):1713–1721PubMedCrossRefGoogle Scholar
  8. Pizzo PA, Poplack DG (eds) Ch 29. In: Renal tumors: principles and practice of pediatric oncology. Lippincott WilliamsGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Department of PediatricsSt. John’s Medical College HospitalBangaloreIndia
  2. 2.Division of Pediatric Oncology, Montreal Children’s HospitalMcGill UniversityMontrealCanada

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