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Nanomaterials for Positive Contrast Imaging of MR-Visible Implants

  • I. Slabu
  • G. Güntherodt
  • T. Schmitz-Rode
  • M. Hodenius
  • N. Krämer
  • G. A. Krombach
  • J. Otto
  • U. Klinge
  • M. Baumann
Conference paper
Part of the IFMBE Proceedings book series (IFMBE, volume 25/8)

Abstract

Each year, about 1.5 million textile meshes are implanted worldwide for abdominal hernia repair. In 10 to 30 % of the cases complications, which are often determined by the mesh, occur. A visualization of the implant helps the surgeon to identify the cause of the suffering and to choose the right treatment. Therefore, superparamagnetic nanoparticles (SPM) are distributed within the filaments of the mesh, which can be then visualized in MRT. Because of the induced susceptibility artefacts of the SPM, the implant can be detected as signal voids in the MR image. Consequently, a homogenous distribution of the SPM within the mesh is of great importance. In this work, the magnetic properties of the particles and of the mesh are analyzed and a method of detecting the incorporated magnetic particles within the filaments of the mesh is developed.

Keywords

superparamagnetic nanoparticles magnetic resonance imaging inversion recovery with ON-resonant water suppression superconducting quantum interference device magnetic force microscopy 

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Copyright information

© International Federation for Medical and Biological Engineering 2009

Authors and Affiliations

  • I. Slabu
    • 1
  • G. Güntherodt
    • 2
  • T. Schmitz-Rode
    • 1
  • M. Hodenius
    • 1
  • N. Krämer
    • 3
  • G. A. Krombach
    • 3
  • J. Otto
    • 4
  • U. Klinge
    • 1
    • 4
  • M. Baumann
    • 1
  1. 1.Applied Medical Engineering, Medical Faculty, Helmholtz InstituteRWTH Aachen UniversityGermany
  2. 2.II. Physical InstituteRWTH Aachen UniversityGermany
  3. 3.Department for Radiology, Medical FacultyRWTH Aachen UniversityGermany
  4. 4.Department for Surgery, Medical FacultyRWTH Aachen UniversityGermany

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