Mechanisms of Phototoxic and Photoallergic Reactions

  • Renz Mang
  • Helger Stege
  • Jean Krutmann


Solar radiation represents an important environmental stress for human skin. The biological reactions resulting from this interaction leads to physiological and pathological reactions such as an increased photosensitivity. The present chapter focuses on the mechanisms underlying photosensitivity, especially phototoxic and photoallergic reactions caused by exogenous and endogenous chemicals, especially drugs.


Tiaprofenic Acid Photosensitivity Reaction PUVA Therapy Phototoxic Reaction Fluorine Substituent 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  1. 1.Gemeinschaftspraxis für Dermatologie Venerologie, Allergologie, ProktologieWuppertalGermany
  2. 2.Depatement of DermatologyKlinikum LippeDetmoldGermany
  3. 3.Institut für umweltmedizinische Forschung, an der Heinrich-Heine-Universität Düsseldorf gGmbHDüsseldorfGermany

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