Plastics Completely Synthesized by Bacteria: Polyhydroxyalkanoates

  • Guo-Qiang Chen
Part of the Microbiology Monographs book series (MICROMONO, volume 14)


Polyhydroxyalkanoates (PHA) produced by many bacteria have been investigated by microbiologists, molecular biologists, biochemists, chemical engineers, chemists, polymer experts, and medical researchers over the past many years. Applications of PHA as bioplastics, fine chemicals, implant biomaterials, medicines, and biofuels have been developed. Companies have been established or involved in PHA-related R&D as well as large-scale production. PHA synthesis has been found to improve the robustness of non-PHA-producing microorganisms and to regulate bacterial metabolism, leading to yield improvement for some bacterial fermentation products. In addition, amphiphilic proteins related to PHA synthesis including PhaP, PhaZ, and PhaC have been found to be useful for achieving protein purification and even specific drug targeting. It has become clear that PHA and its related technologies are forming an industrial value chain ranging from fermentation, materials, and energy to medical fields.


Block Copolymer Isothermal Crystallization Cupriavidus Necator Pseudomonas Oleovorans Hydroxyoctanoic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  1. 1.Department of Biological Sciences and BiotechnologyTsinghua UniversityBeijingChina

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