Nonself Detection in a Two-Component Cellular Frustrated System

  • F. Vistulo de Abreu
  • P. Mostardinha
Part of the Lecture Notes in Computer Science book series (LNCS, volume 5666)


The cellular frustration concept was first introduced in an ICARIS conference [1] as an alternative approach to accomplish specific and prompt intrusion detection in highly diverse systems. Cellular frustration uses two main assumptions: 1) that cells’ activation are better modeled as cellular decisions and 2) that these cells’ decisions require a finite amount of time to be triggered. These two assumptions have been gaining experimental support. It is now well established that T cells activation requires a considerable amount of time [2]. Experimental observations also suggest that interactions of T cells with APCs could be better modeled as cellular decisions rather than conventional probabilistic reactions [3],[4]. As a result from these assumptions the cellular frustration framework (CFF) is capable of reconciling two apparently opposing phenomena, namely high reactivity against nonself with total tolerance towards self [4].


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Copyright information

© Springer-Verlag Berlin Heidelberg 2009

Authors and Affiliations

  • F. Vistulo de Abreu
    • 1
  • P. Mostardinha
    • 1
  1. 1.Departamento de FísicaUniversidade de AveiroAveiro

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