Using UML to Model EAE and Its Regulatory Network

  • Mark Read
  • Jon Timmis
  • Paul S. Andrews
  • Vipin Kumar
Part of the Lecture Notes in Computer Science book series (LNCS, volume 5666)

Abstract

Experimental Autoimmune Encephalomyelitis (EAE) is an autoimmune disease in mice which serves as a model for multiple sclerosis in humans [4,5]. The disease constitutes the direction of immunity towards myelin, an insulatory material that covers neurons. The consequential damage to the central nervous system (CNS) can lead to paralysis and death [6].

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Copyright information

© Springer-Verlag Berlin Heidelberg 2009

Authors and Affiliations

  • Mark Read
    • 1
  • Jon Timmis
    • 1
    • 2
  • Paul S. Andrews
    • 1
  • Vipin Kumar
    • 3
  1. 1.Department of Computer ScienceUniversity of YorkUK
  2. 2.Department of ElectronicsUniversity of YorkUK
  3. 3.Laboratory of AutoimmunityTorrey Pines Institute for Molecular StudiesUSA

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