Agent Based Modeling of Lung Metastasis-Immune System Competition

  • Marzio Pennisi
  • Francesco Pappalardo
  • Santo Motta
Part of the Lecture Notes in Computer Science book series (LNCS, volume 5666)

Abstract

The Triplex vaccine is a cell vaccine developed as an immunopreventive approach to breast cancer. Recent studies showed that the same vaccine has a considerable therapeutic effect against lung metastases derived by mammary carcinoma[1].

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Nanni, P., Nicoletti, G., Palladini, A., et al.: Antimetastatic Activity of a Preventive Cancer Vaccine. Cancer Research 67, 11037 (2007)CrossRefGoogle Scholar
  2. 2.
    Pappalardo, F., Lollini, P., Castiglione, F., Motta, S.: Modeling and simulation of cancer immunoprevention vaccine. Bioinformatics 21, 2891–2897 (2005)CrossRefGoogle Scholar
  3. 3.
    Kendall, W.S.: The Size Distribution of Human Hematogenous Metastases. J. theor. Biol. 211, 2938 (2001)Google Scholar
  4. 4.
    Mallet, D.G., de Pillis, L.G.: A cellular automata model of tumor immune system interactions. Journal of Theoretical Biology 239(3), 334–350 (2006)MathSciNetCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2009

Authors and Affiliations

  • Marzio Pennisi
    • 1
  • Francesco Pappalardo
    • 1
  • Santo Motta
    • 1
  1. 1.Department of Mathematics and Computer ScienceUniversity of CataniaItaly

Personalised recommendations