GREAT: Gene Regulation EvAluation Tool

  • Catia Machado
  • Hugo Bastos
  • Francisco Couto
Part of the Lecture Notes in Computer Science book series (LNCS, volume 5518)


Our understanding of biological systems is highly dependent on the study of the mechanisms that regulate genetic expression. In this paper we present a tool to evaluate scientific papers that potentially describe Saccharomyces cerevisiae gene regulations, following the identification of transcription factors in abstracts using text mining techniques. GREAT evaluates the probability of a given gene-transcription factor pair corresponding to a gene regulation based on data retrieved from public biological databases.


Gene Ontology gene regulations Saccharomyces cerevisiae text mining 


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Copyright information

© Springer-Verlag Berlin Heidelberg 2009

Authors and Affiliations

  • Catia Machado
    • 1
  • Hugo Bastos
    • 1
  • Francisco Couto
    • 1
  1. 1.Department of Informatics, Faculty of SciencesUniversity of LisbonLisbonPortugal

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