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Radiological Imaging in Arthritis: Current Status and Limitations

  • Hans Van der Wall
  • Robert Loneragan
  • Louise Wong
  • Les Barnsley
  • Siri Kannangara
Chapter

Abstract

Knowledge of the rheumatic disease has grown immeasurably since the early twentieth century, changing the criteria and classification of the diseases. The rheumatic diseases have broadly been classified according to positivity for rheumatoid factor. The immunological and genetic basis of these diseases has been refined, and the pathophysiology elucidated to a large extent. These changes have been reflected in the advances in imaging of the rheumatic diseases, particularly with the increasing adoption of MRI. MRI criteria have become accepted as part of the early disease classification, allowing the commencement of therapy before the radiological or clinical evidence of disease manifests, thus allowing treatment at a potentially reversible stage. The evidence for these changes in the paradigm of imaging the rheumatic disease will be presented and assessed together with potential shortcomings.

Keywords

Magnetic Resonance Image Ankylose Spondylitis Bone Erosion Bone Marrow Oedema Joint Space Narrowing 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Agudelo CA, Wise CM (2001) Gout: diagnosis, pathogenesis, and clinical manifestations. Curr Opin Rheumatol 13(3):234–239PubMedCrossRefGoogle Scholar
  2. Altenbernd J, Bitu S, Lemburg S et al (2009) Vertebral fractures in patients with ankylosing spondylitis: a retrospective analysis of 66 patients. Rofo 181(1):45–53PubMedCrossRefGoogle Scholar
  3. Amin S, LaValley MP, Guermazi A et al (2005) The relationship between cartilage loss on magnetic resonance imaging and radiographic progression in men and women with knee osteoarthritis. Arthritis Rheum 52(10):3152–3159PubMedCrossRefGoogle Scholar
  4. Amor B, Cherot A, Delbarre F (1977) Hydroxyapatite rheumatism (multiple tendon calcification disease). I. Clinical study. Rev Rhum Mal Osteoartic 44(5):301–308PubMedGoogle Scholar
  5. Anandacoomarasamy A, Leibman S, Smith G et al (2010) Weight loss in obese people has structure-modifying effects on knee articular cartilage (abstract). EULAR Rome OP0159Google Scholar
  6. Arnett FC, Edworthy SM, Bloch DA et al (1988) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31(3):315–324PubMedCrossRefGoogle Scholar
  7. Balint G, Szebenyi B (2000) Hereditary disorders mimicking and/or causing premature osteoarthritis. Baillieres Best Pract Res Clin Rheumatol 14(2):219–250PubMedCrossRefGoogle Scholar
  8. Barozzi L, Olivieri I, De Matteis M et al (1998) Seronegative spondylarthropathies: imaging of spondylitis, enthesitis and dactylitis. Eur J Radiol 27(Suppl 1):S12–S17PubMedCrossRefGoogle Scholar
  9. Benedek TG (2009) How did ankylosing spondylitis become a separate disease? Clin Exp Rheumatol 27(4 Suppl 55):S3–S9PubMedGoogle Scholar
  10. Benjamin M, Toumi H, Suzuki D et al (2007) Microdamage and altered vascularity at the enthesis-bone interface provides an anatomic explanation for bone involvement in the HLA-B27-associated spondylarthritides and allied disorders. Arthritis Rheum 56(1):224–233PubMedCrossRefGoogle Scholar
  11. Benjamin M, Toumi H, Suzuki D et al (2009) Evidence for a distinctive pattern of bone formation in enthesophytes. Ann Rheum Dis 68(6):1003–1010PubMedCrossRefGoogle Scholar
  12. Bennett AN, McGonagle D, O’Connor P et al (2008) Severity of baseline magnetic resonance imaging-evident sacroiliitis and HLA-B27 status in early inflammatory back pain predict radiographically evident ankylosing spondylitis at eight years. Arthritis Rheum 58(11):3413–3418PubMedCrossRefGoogle Scholar
  13. Bennett AN, Rehman A, Hensor EM et al (2009) Evaluation of the diagnostic utility of spinal magnetic resonance imaging in axial spondylarthritis. Arthritis Rheum 60(5):1331–1341PubMedCrossRefGoogle Scholar
  14. Bennett AN, Marzo-Ortega H, Rehman A et al (2010a) The evidence for whole-spine MRI in the assessment of axial spondyloarthropathy. Rheumatology (Oxford) 49(3):426–432CrossRefGoogle Scholar
  15. Bennett AN, Rehman A, Hensor EM et al (2010b) The fatty Romanus lesion: a non-inflammatory spinal MRI lesion specific for axial spondyloarthropathy. Ann Rheum Dis 69(5):891–894PubMedCrossRefGoogle Scholar
  16. Benton N, Stewart N, Crabbe J et al (2004) MRI of the wrist in early rheumatoid arthritis can be used to predict functional outcome at 6 years. Ann Rheum Dis 63(5):555–561PubMedCrossRefGoogle Scholar
  17. Biswal S, Resnick DL, Hoffman JM et al (2007) Molecular imaging: integration of molecular imaging into the musculoskeletal imaging practice. Radiology 244(3):651–671PubMedCrossRefGoogle Scholar
  18. Bloch C, Hermann G, Yu T (1980) A radiologic reevaluation of gout: a study of 2,000 patients. Am J Roentgenol 134:781Google Scholar
  19. Boutry N, Cotten A (2010) Contribution of ultrasonography in inflammatory rheumatic disorders (rheumatoid arthritis, polymyalgia rheumatica and spondyloarthropathies). Rev Med Interne 31(1):29–40PubMedCrossRefGoogle Scholar
  20. Boutry N, Larde A, Lapegue F et al (2003) Magnetic resonance imaging appearance of the hands and feet in patients with early rheumatoid arthritis. J Rheumatol 30(4):671–679PubMedGoogle Scholar
  21. Boutry N, Morel M, Flipo RM et al (2007) Early rheumatoid arthritis: a review of MRI and sonographic findings. AJR Am J Roentgenol 189(6):1502–1509PubMedCrossRefGoogle Scholar
  22. Boutry N, do Carmo CC, Flipo RM et al (2009) Early rheumatoid arthritis and its differentiation from other joint abnormalities. Eur J Radiol 71(2):217–224PubMedCrossRefGoogle Scholar
  23. Bouvet JP, le Parc JM, Michalski B et al (1985) Acute neck pain due to calcifications surrounding the odontoid process: the crowned dens syndrome. Arthritis Rheum 28(12):1417–1420PubMedCrossRefGoogle Scholar
  24. Brandt J, Haibel H, Cornely D et al (2000) Successful treatment of active ankylosing spondylitis with the anti-tumor necrosis factor alpha monoclonal antibody infliximab. Arthritis Rheum 43(6):1346–1352PubMedCrossRefGoogle Scholar
  25. Brandt J, Sieper J, Braun J (2002) Infliximab in the treatment of active and severe ankylosing spondylitis. Clin Exp Rheumatol 20(6 Suppl 28):S106–S110PubMedGoogle Scholar
  26. Braun J (2009) Therapy of spondyloarthritides. Adv Exp Med Biol 649:133–147PubMedCrossRefGoogle Scholar
  27. Braun J, van der Heijde D (2002) Imaging and scoring in ankylosing spondylitis. Best Pract Res Clin Rheumatol 16(4):573–604PubMedGoogle Scholar
  28. Braun J, Bollow M, Remlinger G et al (1998) Prevalence of spondylarthropathies in HLA-B27 positive and negative blood donors. Arthritis Rheum 41(1):58–67PubMedCrossRefGoogle Scholar
  29. Braun J, Breban M, Maksymowych WP (2002a) Therapy for ankylosing spondylitis: new treatment modalities. Best Pract Res Clin Rheumatol 16(4):631–651PubMedGoogle Scholar
  30. Braun J, Golder W, Bollow M et al (2002b) Imaging and scoring in ankylosing spondylitis. Clin Exp Rheumatol 20(6 Suppl 28):S178–S184PubMedGoogle Scholar
  31. Braun J, Landewe R, Hermann KG et al (2006) Major reduction in spinal inflammation in patients with ankylosing spondylitis after treatment with infliximab: results of a multicenter, randomized, double-blind, placebo-controlled magnetic resonance imaging study. Arthritis Rheum 54(5):1646–1652PubMedCrossRefGoogle Scholar
  32. Braun J, Sieper J, Pincus T (2009) A systematic comparison between rheumatoid arthritis and ankylosing spondylitis: an introduction. Clin Exp Rheumatol 27(4 Suppl 55):S1–S2PubMedGoogle Scholar
  33. Bron JL, de Vries MK, Snieders MN et al (2009) Discovertebral (Andersson) lesions of the spine in ankylosing spondylitis revisited. Clin Rheumatol 28(8):883–892PubMedCrossRefGoogle Scholar
  34. Buckland-Wright C (1999) Radiographic assessment of osteoarthritis: comparison between existing methodologies. Osteoarthritis Cartilage 7(4):430–433PubMedCrossRefGoogle Scholar
  35. Carrera GF, Foley WD, Kozin F et al (1981) CT of sacroiliitis. AJR Am J Roentgenol 136(1):41–46PubMedGoogle Scholar
  36. Carter JD, Kedar RP, Anderson SR et al (2009) An analysis of MRI and ultrasound imaging in patients with gout who have normal plain radiographs. Rheumatology (Oxford) 48(11):1442–1446CrossRefGoogle Scholar
  37. Choi MH, MacKenzie JD, Dalinka MK (2006) Imaging features of crystal-induced arthropathy. Rheum Dis Clin North Am 32(2):427–446, viiiPubMedCrossRefGoogle Scholar
  38. Colistro R, Torreggiani W, Lyburn I et al (2002) Unenhanced helical CT in the investigation of acute flank pain. Clin Radiol 57:435PubMedCrossRefGoogle Scholar
  39. Conaghan P, Bird P, Ejbjerg B et al (2005) The EULAR-OMERACT rheumatoid arthritis MRI reference image atlas: the metacarpophalangeal joints. Ann Rheum Dis 64(Suppl 1):i11–i21PubMedCrossRefGoogle Scholar
  40. D’Lima DD, Hashimoto S, Chen PC et al (2001a) Cartilage injury induces chondrocyte apoptosis. J Bone Joint Surg Am 83-A Suppl 2(Pt 1):19–21PubMedGoogle Scholar
  41. D’Lima DD, Hashimoto S, Chen PC et al (2001b) Prevention of chondrocyte apoptosis. J Bone Joint Surg Am 83-A Suppl 2(Pt 1):25–26PubMedGoogle Scholar
  42. Dahaghin S, Bierma-Zeinstra SM, Reijman M et al (2005) Does hand osteoarthritis predict future hip or knee osteoarthritis? Arthritis Rheum 52(11):3520–3527PubMedCrossRefGoogle Scholar
  43. Dale K, Vinje O (1985) Radiography of the spine and sacroiliac joints in ankylosing spondylitis and psoriasis. Acta Radiol 26:145–159Google Scholar
  44. Davis JC Jr, Van Der Heijde D, Braun J et al (2003) Recombinant human tumor necrosis factor receptor (etanercept) for treating ankylosing spondylitis: a randomized, controlled trial. Arthritis Rheum 48(11):3230–3236PubMedCrossRefGoogle Scholar
  45. Doherty M (2000) Genetics of hand osteoarthritis. Osteoarthritis Cartilage 8(Suppl A):S8–S10PubMedGoogle Scholar
  46. Dougados M, van der Linden S, Juhlin R et al (1991) The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy. Arthritis Rheum 34(10):1218–1227PubMedCrossRefGoogle Scholar
  47. Duer A, Ostergaard M, Horslev-Petersen K et al (2008) Magnetic resonance imaging and bone scintigraphy in the differential diagnosis of unclassified arthritis. Ann Rheum Dis 67(1):48–51PubMedCrossRefGoogle Scholar
  48. Dye SF, Chew MH (1994) The use of scintigraphy to detect increased osseous metabolic activity about the knee. Instr Course Lect 43:453–469PubMedGoogle Scholar
  49. Eckstein F, Cicuttini F, Raynauld JP et al (2006) Magnetic resonance imaging (MRI) of articular cartilage in knee osteoarthritis (OA): morphological assessment. Osteoarthritis Cartilage 14(Suppl A):A46–A75PubMedCrossRefGoogle Scholar
  50. Eckstein F, Wirth W, Hudelmaier M et al (2008) Patterns of femorotibial cartilage loss in knees with neutral, varus, and valgus alignment. Arthritis Rheum 59(11):1563–1570PubMedCrossRefGoogle Scholar
  51. Ejbjerg B, Narvestad E, Rostrup E et al (2004) Magnetic resonance imaging of wrist and finger joints in healthy subjects occasionally shows changes resembling erosions and synovitis as seen in rheumatoid arthritis. Arthritis Rheum 50(4):1097–1106PubMedCrossRefGoogle Scholar
  52. Ejbjerg B, McQueen F, Lassere M et al (2005) The EULAR-OMERACT rheumatoid arthritis MRI reference image atlas: the wrist joint. Ann Rheum Dis 64(Suppl 1):i23–i47PubMedCrossRefGoogle Scholar
  53. Englund M, Paradowski PT, Lohmander LS (2004) Association of radiographic hand osteoarthritis with radiographic knee osteoarthritis after meniscectomy. Arthritis Rheum 50(2):469–475PubMedCrossRefGoogle Scholar
  54. Englund M, Guermazi A, Roemer FW et al (2009) Meniscal tear in knees without surgery and the development of radiographic osteoarthritis among middle-aged and elderly persons: the Multicenter Osteoarthritis Study. Arthritis Rheum 60(3):831–839PubMedCrossRefGoogle Scholar
  55. Faure G, Daculsi G (1983) Calcified tendinitis: a review. Ann Rheum Dis 42(Suppl):149–153CrossRefGoogle Scholar
  56. Felson DT (2004) Risk factors for osteoarthritis: understanding joint vulnerability. Clin Orthop Relat Res 427 (Suppl):S16–S21Google Scholar
  57. Felson DT (2009) Developments in the clinical understanding of osteoarthritis. Arthritis Res Ther 11(1):203PubMedCrossRefGoogle Scholar
  58. Felson DT, Chaisson CE, Hill CL et al (2001) The association of bone marrow lesions with pain in knee osteoarthritis. Ann Intern Med 134(7):541–549PubMedGoogle Scholar
  59. Felson DT, McLaughlin S, Goggins J et al (2003) Bone marrow edema and its relation to progression of knee osteoarthritis. Ann Intern Med 139(5 Pt 1):330–336PubMedGoogle Scholar
  60. Felson DT, Niu J, Guermazi A et al (2007) Correlation of the development of knee pain with enlarging bone marrow lesions on magnetic resonance imaging. Arthritis Rheum 56(9):2986–2992PubMedCrossRefGoogle Scholar
  61. Felson DT, Nevitt MC, Yang M et al (2008) A new approach yields high rates of radiographic progression in knee osteoarthritis. J Rheumatol 35(10):2047–2054PubMedGoogle Scholar
  62. Feydy A, Liote F, Carlier R et al (2006) Cervical spine and crystal-associated diseases: imaging findings. Eur Radiol 16(2):459–468PubMedCrossRefGoogle Scholar
  63. Fitzgerald GK, Piva SR, Irrgang JJ (2004) Reports of joint instability in knee osteoarthritis: its prevalence and relationship to physical function. Arthritis Rheum 51(6):941–946PubMedCrossRefGoogle Scholar
  64. Forestier J, Rotes-Querol J (1950) Senile ankylosing hyperostosis of the spine. Ann Rheum Dis 9(4):321–330PubMedCrossRefGoogle Scholar
  65. Gabriel SE, Crowson CS, Kremers HM et al (2003) Survival in rheumatoid arthritis: a population-based analysis of trends over 40 years. Arthritis Rheum 48(1):54–58PubMedCrossRefGoogle Scholar
  66. Geijer M, Gothlin GG, Gothlin JH (2007) The clinical utility of computed tomography compared to conventional radiography in diagnosing sacroiliitis. A retrospective study on 910 patients and literature review. J Rheumatol 34(7):1561–1565PubMedGoogle Scholar
  67. Goto S, Umehara J, Aizawa T et al (2007) Crowned Dens syndrome. J Bone Joint Surg Am 89(12):2732–2736PubMedCrossRefGoogle Scholar
  68. Guglielmi G, Scalzo G, Cascavilla A et al (2009) Imaging of the sacroiliac joint involvement in seronegative spondylarthropathies. Clin Rheumatol 28(9):1007–1019PubMedCrossRefGoogle Scholar
  69. Haavardsholm EA, Ostergaard M, Ejbjerg BJ et al (2005) Reliability and sensitivity to change of the OMERACT rheumatoid arthritis magnetic resonance imaging score in a multireader, longitudinal setting. Arthritis Rheum 52(12):3860–3867PubMedCrossRefGoogle Scholar
  70. Haavardsholm EA, Boyesen P, Ostergaard M et al (2008) Magnetic resonance imaging findings in 84 patients with early rheumatoid arthritis: bone marrow oedema predicts erosive progression. Ann Rheum Dis 67(6):794–800PubMedCrossRefGoogle Scholar
  71. Hawker GA, Stewart L, French MR et al (2008) Understanding the pain experience in hip and knee osteoarthritis–an OARSI/OMERACT initiative. Osteoarthritis Cartilage 16(4):415–422PubMedCrossRefGoogle Scholar
  72. Hench P (1936) The diagnosis of gout and gouty arthritis. J Lab Clin Med 220:48Google Scholar
  73. Hernandez-Molina G, Neogi T, Hunter DJ et al (2008) The association of bone attrition with knee pain and other MRI features of osteoarthritis. Ann Rheum Dis 67(1):43–47PubMedCrossRefGoogle Scholar
  74. Hill CL, Gale DR, Chaisson CE et al (2003) Periarticular lesions detected on magnetic resonance imaging: prevalence in knees with and without symptoms. Arthritis Rheum 48(10):2836–2844PubMedCrossRefGoogle Scholar
  75. Hill CL, Hunter DJ, Niu J et al (2007) Synovitis detected on magnetic resonance imaging and its relation to pain and cartilage loss in knee osteoarthritis. Ann Rheum Dis 66(12):1599–1603PubMedCrossRefGoogle Scholar
  76. Horisberger M, Valderrabano V, Hintermann B (2009) Posttraumatic ankle osteoarthritis after ankle-related fractures. J Orthop Trauma 23(1):60–67PubMedCrossRefGoogle Scholar
  77. Hoving JL, Buchbinder R, Hall S et al (2004) A comparison of magnetic resonance imaging, sonography, and radiography of the hand in patients with early rheumatoid arthritis. J Rheumatol 31(4):663–675PubMedGoogle Scholar
  78. Hunter DJ, Zhang Y, Niu J et al (2006a) Increase in bone marrow lesions associated with cartilage loss: a longitudinal magnetic resonance imaging study of knee osteoarthritis. Arthritis Rheum 54(5):1529–1535PubMedCrossRefGoogle Scholar
  79. Hunter DJ, Zhang YQ, Tu X et al (2006b) Change in joint space width: hyaline articular cartilage loss or alteration in meniscus? Arthritis Rheum 54(8):2488–2495PubMedCrossRefGoogle Scholar
  80. Imhof H, Nobauer-Huhmann IM, Gahleitner A et al (2002) Pathophysiology and imaging in inflammatory and blastomatous synovial diseases. Skeletal Radiol 31(6):313–333PubMedCrossRefGoogle Scholar
  81. Iovane A, Midiri M, Finazzo M et al (1998) Magnetic resonance imaging of seronegative sacroiliitis. Radiol Med 96:185–189PubMedGoogle Scholar
  82. Jimenez SA (1991) Molecular biological approaches to the study of heritable osteoarthritis. J Rheumatol Suppl 27:7–9PubMedGoogle Scholar
  83. Kirkup JR, Vidigal E, Jacoby RK (1977) The hallux and rheumatoid arthritis. Acta Orthop Scand 48(5):527–544PubMedCrossRefGoogle Scholar
  84. Kitaoka HB (1989) Rheumatoid hindfoot. Orthop Clin North Am 20(4):593–604PubMedGoogle Scholar
  85. Knupp M, Pagenstert GI, Barg A et al (2009) SPECT-CT compared with conventional imaging modalities for the assessment of the varus and valgus malaligned hindfoot. J Orthop Res 27(11):1461–1466PubMedCrossRefGoogle Scholar
  86. Koivikko MP, Koskinen SK (2008) MRI of cervical spine injuries complicating ankylosing spondylitis. Skeletal Radiol 37(9):813–819PubMedCrossRefGoogle Scholar
  87. Kortekaas M, Kwok WY, Reijnierse M et al (2010) Pain in hand osteoarthritis is associated with inflammation – the value of ultrasound (abstract). EULAR Rome OPOO35Google Scholar
  88. Landewe RB, Boers M, Verhoeven AC et al (2002) COBRA combination therapy in patients with early rheumatoid arthritis: long-term structural benefits of a brief intervention. Arthritis Rheum 46(2):347–356PubMedCrossRefGoogle Scholar
  89. Larsen A (1995) How to apply Larsen score in evaluating radiographs of rheumatoid arthritis in long-term studies. J Rheumatol 22(10):1974–1975PubMedGoogle Scholar
  90. Larsen A, Dale K, Eek M (1977) Radiographic evaluation of rheumatoid arthritis and related conditions by standard reference films. Acta Radiol Diagn (Stockh) 18(4):481–491Google Scholar
  91. Lawrence RC, Helmick CG, Arnett FC et al (1998) Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States. Arthritis Rheum 41(5):778–799PubMedCrossRefGoogle Scholar
  92. Lawson T, Foley W, Carrera G et al (1982) The sacroiliac joints: anatomic, plain roentgenographic, and computed tomographic analysis. J Comput Assist Tomogr 6:307–314PubMedCrossRefGoogle Scholar
  93. Lehtinen JT, Kaarela K, Belt EA et al (2001) Radiographic joint space in rheumatoid elbow joints. A 15-year prospective follow-up study in 74 patients. Rheumatology (Oxford) 40(10):1141–1145CrossRefGoogle Scholar
  94. Leisen JC, Austad ED, Bluhm GB et al (1980) The tophus in calcium pyrophosphate deposition disease. JAMA 244(15):1711–1712PubMedCrossRefGoogle Scholar
  95. Levy G, Chow C, Cimmino MA et al (2009) RA Imaging Study Group: which imaging in rheumatoid arthritis? Joint Bone Spine 76(4):438–439PubMedCrossRefGoogle Scholar
  96. Linke R, Kuwert T, Uder M et al (2010) Skeletal SPECT/CT of the peripheral extremities. AJR Am J Roentgenol 194(4):W329–W335PubMedCrossRefGoogle Scholar
  97. Maksymowych WP, Jhangri GS, Lambert RG et al (2002) Infliximab in ankylosing spondylitis: a prospective observational inception cohort analysis of efficacy and safety. J Rheumatol 29(5):959–965PubMedGoogle Scholar
  98. Martel W, Hayes JT, Duff IF (1965) The pattern of bone erosion in the hand and wrist in rheumatoid arthritis. Radiology 84:204–214PubMedGoogle Scholar
  99. Marzo-Ortega H, Tanner SF, Rhodes LA et al (2009) Magnetic resonance imaging in the assessment of metacarpophalangeal joint disease in early psoriatic and rheumatoid arthritis. Scand J Rheumatol 38(2):79–83PubMedCrossRefGoogle Scholar
  100. McCarty D (1966) Pseudogout, articular chondrocalcinosis, 7th edn. Lea & Febiger, PhiladelphiaGoogle Scholar
  101. McCarty DJ (1986) Arthropathies associated with calcium-containing crystals. Hosp Pract (Off Ed) 21(10):109–115, 18–20Google Scholar
  102. McCarty DJ, Pepe PF (1972) Erythrocyte neutral inorganic pyrophosphatase in pseudogout. J Lab Clin Med 79(2):277–284PubMedGoogle Scholar
  103. McGonagle D (2010) The history of erosions in rheumatoid arthritis: are erosions history? Arthritis Rheum 62(2):312–315PubMedCrossRefGoogle Scholar
  104. McGonagle D, Tan AL (2008) What magnetic resonance imaging has told us about the pathogenesis of rheumatoid arthritis – the first 50 years. Arthritis Res Ther 10(5):222PubMedCrossRefGoogle Scholar
  105. McQueen FM, Stewart N, Crabbe J et al (1998) Magnetic resonance imaging of the wrist in early rheumatoid arthritis reveals a high prevalence of erosions at four months after symptom onset. Ann Rheum Dis 57(6):350–356PubMedCrossRefGoogle Scholar
  106. McQueen F, Lassere M, Edmonds J et al (2003a) OMERACT rheumatoid arthritis magnetic resonance imaging studies summary of OMERACT 6 MR imaging module. J Rheumatol 30(6):1387–1392PubMedGoogle Scholar
  107. McQueen FM, Benton N, Perry D et al (2003b) Bone edema scored on magnetic resonance imaging scans of the dominant carpus at presentation predicts radiographic joint damage of the hands and feet six years later in patients with rheumatoid arthritis. Arthritis Rheum 48(7):1814–1827PubMedCrossRefGoogle Scholar
  108. Mizumura T, Momohara S, Tomatsu T et al (2000) Radiological evaluation of foot deformities in rheumatoid arthritis. Ryumachi 40(6):891–897PubMedGoogle Scholar
  109. Moller Dohn U, Boonen A, Hetland ML et al (2009) Erosive progression is minimal, but erosion healing rare, in patients with rheumatoid arthritis treated with adalimumab. A 1 year investigator-initiated follow-up study using high-resolution computed tomography as the primary outcome measure. Ann Rheum Dis 68(10):1585–1590PubMedCrossRefGoogle Scholar
  110. Narvaez JA, Narvaez J, Serrallonga M et al (2008) Cervical spine involvement in rheumatoid arthritis: correlation between neurological manifestations and magnetic resonance imaging findings. Rheumatology (Oxford) 47(12):1814–1819CrossRefGoogle Scholar
  111. Nevitt MC, Peterfy C, Guermazi A et al (2007) Longitudinal performance evaluation and validation of fixed-flexion radiography of the knee for detection of joint space loss. Arthritis Rheum 56(5):1512–1520PubMedCrossRefGoogle Scholar
  112. Niu J, Zhang YQ, Torner J et al (2009) Is obesity a risk factor for progressive radiographic knee osteoarthritis? Arthritis Rheum 61(3):329–335PubMedCrossRefGoogle Scholar
  113. O’Dell JR (1996) Combination DMARD therapy for rheumatoid arthritis: a step closer to the goal. Ann Rheum Dis 55(11):781–783PubMedCrossRefGoogle Scholar
  114. Olivieri I, D’Angelo S, Palazzi C et al (2009) Diffuse idiopathic skeletal hyperostosis: differentiation from ankylosing spondylitis. Curr Rheumatol Rep 11(5):321–328PubMedCrossRefGoogle Scholar
  115. Ostergaard M, Hansen M, Stoltenberg M et al (1999) Magnetic resonance imaging-determined synovial membrane volume as a marker of disease activity and a predictor of progressive joint destruction in the wrists of patients with rheumatoid arthritis. Arthritis Rheum 42(5):918–929PubMedCrossRefGoogle Scholar
  116. Ostergaard M, Peterfy C, Conaghan P et al (2003) OMERACT rheumatoid arthritis magnetic resonance imaging studies. Core set of MRI acquisitions, joint pathology definitions, and the OMERACT RA-MRI scoring system. J Rheumatol 30(6):1385–1386PubMedGoogle Scholar
  117. Palosaari K, Vuotila J, Takalo R et al (2006) Bone oedema predicts erosive progression on wrist MRI in early RA – a 2-yr observational MRI and NC scintigraphy study. Rheumatology (Oxford) 45(12):1542–1548CrossRefGoogle Scholar
  118. Pennes DR, Martel W (1986) Hyperuricemia and gout. Semin Roentgenol 21(4):245–255PubMedCrossRefGoogle Scholar
  119. Perry D, Stewart N, Benton N et al (2005) Detection of erosions in the rheumatoid hand; a comparative study of multidetector computerized tomography versus magnetic resonance scanning. J Rheumatol 32(2):256–267PubMedGoogle Scholar
  120. Potter TA (1969) Mechanisms of deformity of the rheumatoid arthritic knee. Surg Clin North Am 49(4):889–893PubMedGoogle Scholar
  121. Puhakka KB, Jurik AG, Egund N et al (2003) Imaging of sacroiliitis in early seronegative spondylarthropathy. Assessment of abnormalities by MR in comparison with radiography and CT. Acta Radiol 44(2):218–229PubMedCrossRefGoogle Scholar
  122. Puhakka KB, Jurik AG, Schiottz-Christensen B et al (2004a) Magnetic resonance imaging of sacroiliitis in early seronegative spondylarthropathy. Abnormalities correlated to clinical and laboratory findings. Rheumatology (Oxford) 43(2):234–237CrossRefGoogle Scholar
  123. Puhakka KB, Jurik AG, Schiottz-Christensen B et al (2004b) MRI abnormalities of sacroiliac joints in early spondylarthropathy: a 1-year follow-up study. Scand J Rheumatol 33(5):332–338PubMedCrossRefGoogle Scholar
  124. Rahmani M, Chegini H, Najafizadeh SR et al (2010) Detection of bone erosion in early rheumatoid arthritis: ultrasonography and conventional radiography versus non-contrast magnetic resonance imaging. Clin Rheumatol 29(8):883–891, Epub 2010 Mar 19PubMedCrossRefGoogle Scholar
  125. Rau R, Herborn G (1995) A modified version of Larsen’s scoring method to assess radiologic changes in rheumatoid arthritis. J Rheumatol 22(10):1976–1982PubMedGoogle Scholar
  126. Redlich K, Hayer S, Maier A et al (2002a) Tumor necrosis factor alpha-mediated joint destruction is inhibited by targeting osteoclasts with osteoprotegerin. Arthritis Rheum 46(3):785–792PubMedCrossRefGoogle Scholar
  127. Redlich K, Hayer S, Ricci R et al (2002b) Osteoclasts are essential for TNF-alpha-mediated joint destruction. J Clin Invest 110(10):1419–1427PubMedGoogle Scholar
  128. Reginato A, Valenzuela F, Martinez V et al (1970) Polyarticular and familial chondrocalcinosis. Arthritis Rheum 13(3):197–213PubMedCrossRefGoogle Scholar
  129. Reichenbach S, Guermazi A, Niu J et al (2008) Prevalence of bone attrition on knee radiographs and MRI in a community-based cohort. Osteoarthritis Cartilage 16(9):1005–1010PubMedCrossRefGoogle Scholar
  130. Resnick D (1974) Arthrography in the evaluation of arthritic disorders of the wrist. Radiology 113(2):331–340PubMedGoogle Scholar
  131. Resnick D (1976) Diffuse idiopathic skeletal hyperostosis (DISH). West J Med 124(5):406–407PubMedGoogle Scholar
  132. Resnick D (1977) Disorders of the axial skeleton which are lesser known, poorly recognized or misunderstood. Bull Rheum Dis 28(2–3):932–939PubMedGoogle Scholar
  133. Resnick D, Shaul SR, Robins JM (1975) Diffuse idiopathic skeletal hyperostosis (DISH): Forestier’s disease with extraspinal manifestations. Radiology 115(3):513–524PubMedGoogle Scholar
  134. Roemer FW, Guermazi A, Javaid MK et al (2009) Change in MRI-detected subchondral bone marrow lesions is associated with cartilage loss: the MOST Study. A longitudinal multicentre study of knee osteoarthritis. Ann Rheum Dis 68(9):1461–1465PubMedCrossRefGoogle Scholar
  135. Rosen A, Weiland AJ (1998) Rheumatoid arthritis of the wrist and hand. Rheum Dis Clin North Am 24(1):101–128PubMedCrossRefGoogle Scholar
  136. Rosenburg E, Arens R (1947) Gout: clinical, pathologic, and roentgenographic observations. Radiology 49:169–177Google Scholar
  137. Rudwaleit M, Sieper J (2005) Infliximab for the treatment of ankylosing spondylitis. Expert Opin Biol Ther 5(8):1095–1109PubMedCrossRefGoogle Scholar
  138. Rudwaleit M, Listing J, Brandt J et al (2004) Prediction of a major clinical response (BASDAI 50) to tumour necrosis factor alpha blockers in ankylosing spondylitis. Ann Rheum Dis 63(6):665–670PubMedCrossRefGoogle Scholar
  139. Rudwaleit M, Schwarzlose S, Hilgert ES et al (2008) MRI in predicting a major clinical response to anti-tumour necrosis factor treatment in ankylosing spondylitis. Ann Rheum Dis 67(9):1276–1281PubMedCrossRefGoogle Scholar
  140. Rudwaleit M, Landewe R, van der Heijde D et al (2009a) The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part I): classification of paper patients by expert opinion including uncertainty appraisal. Ann Rheum Dis 68(6):770–776PubMedCrossRefGoogle Scholar
  141. Rudwaleit M, van der Heijde D, Landewe R et al (2009b) The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann Rheum Dis 68(6):777–783PubMedCrossRefGoogle Scholar
  142. Sato Y, Yasuda T, Konno S et al (2004) Pseudogout showing meningoencephalitic symptoms: crowned dens syndrome. Intern Med 43(9):865–868PubMedCrossRefGoogle Scholar
  143. Selby CL (1984) Acute calcific tendinitis of the hand: an infrequently recognized and frequently misdiagnosed form of periarthritis. Arthritis Rheum 27(3):337–340PubMedCrossRefGoogle Scholar
  144. Shapiro JS (1982) Wrist involvement in rheumatoid swan-neck deformity. J Hand Surg [Am] 7(5):484–491Google Scholar
  145. Shapiro JS (1996) The wrist in rheumatoid arthritis. Hand Clin 12(3):477–498PubMedGoogle Scholar
  146. Sharma L, Eckstein F, Song J et al (2008) Relationship of meniscal damage, meniscal extrusion, malalignment, and joint laxity to subsequent cartilage loss in osteoarthritic knees. Arthritis Rheum 58(6):1716–1726PubMedCrossRefGoogle Scholar
  147. Sharp JT, Van Der Heijde D, Boers M et al (2003) Repair of erosions in rheumatoid arthritis does occur. Results from 2 studies by the OMERACT Subcommittee on Healing of Erosions. J Rheumatol 30(5):1102–1107PubMedGoogle Scholar
  148. Shih TT, Chen PQ, Li YW et al (2001) Spinal fractures and pseudoarthrosis complicating ankylosing spondylitis: MRI manifestation and clinical significance. J Comput Assist Tomogr 25(2):164–170PubMedCrossRefGoogle Scholar
  149. Sieper J (2009) Developments in the scientific and clinical understanding of the spondyloarthritides. Arthritis Res Ther 11(1):208PubMedCrossRefGoogle Scholar
  150. Sieper J, Rudwaleit M, Baraliakos X et al (2009a) The Assessment of SpondyloArthritis international Society (ASAS) handbook: a guide to assess spondyloarthritis. Ann Rheum Dis 68(Suppl 2):ii1–ii44PubMedCrossRefGoogle Scholar
  151. Sieper J, van der Heijde D, Landewe R et al (2009b) New criteria for inflammatory back pain in patients with chronic back pain: a real patient exercise by experts from the Assessment of SpondyloArthritis international Society (ASAS). Ann Rheum Dis 68(6):784–788PubMedCrossRefGoogle Scholar
  152. Stach CM, Bauerle M, Englbrecht M et al (2010) Periarticular bone structure in rheumatoid arthritis patients and healthy individuals assessed by high-resolution computed tomography. Arthritis Rheum 62(2):330–339PubMedGoogle Scholar
  153. Szkudlarek M, Narvestad M, Klarlund M et al (2004) Ultrasonography of the metatarsophalangeal joints in rheumatoid arthritis: comparison with magnetic resonance imaging, conventional radiography, and clinical examination. Arthritis Rheum 50:2103–2112PubMedCrossRefGoogle Scholar
  154. Szkudlarek M, Klarlund M, Narvestad E et al (2006) Ultrasonography of the metacarpophalangeal and proximal interphalangeal joints in rheumatoid arthritis: a comparison with magnetic resonance imaging, conventional radiography, and clinical examination. Arthritis Res Ther 8:R52Google Scholar
  155. Tallroth K (1998) Plain CT of the degenerative lumbar spine. Eur J Radiol 27(3):206–213PubMedCrossRefGoogle Scholar
  156. Tan AL, Tanner SF, Conaghan PG et al (2003) Role of metacarpophalangeal joint anatomic factors in the distribution of synovitis and bone erosion in early rheumatoid arthritis. Arthritis Rheum 48(5):1214–1222PubMedCrossRefGoogle Scholar
  157. Tan AL, Toumi H, Benjamin M et al (2006) Combined high-resolution magnetic resonance imaging and histological examination to explore the role of ligaments and tendons in the phenotypic expression of early hand osteoarthritis. Ann Rheum Dis 65(10):1267–1272PubMedCrossRefGoogle Scholar
  158. Tehranzadeh J, Ashikyan O, Anavim A et al (2006) Enhanced MR imaging of tenosynovitis of hand and wrist in inflammatory arthritis. Skeletal Radiol 35(11):814–822PubMedCrossRefGoogle Scholar
  159. Tomasson G, Aspelund T, Jonsson T et al (2010) The effect of rheumatoid factor on mortality and coronary heart disease. Ann Rheum Dis 69(9):1649–1654, Epub 2009 Jul 23PubMedCrossRefGoogle Scholar
  160. Tublin ME, Murphy ME, Delong DM et al (2002) Conspicuity of renal calculi at unenhanced CT: effects of calculus composition and size and CT technique. Radiology 225(1):91–96PubMedCrossRefGoogle Scholar
  161. Uhthoff HK, Sarkar K, Maynard JA (1976) Calcifying tendinitis: a new concept of its pathogenesis. Clin Orthop Relat Res 118:164–168PubMedGoogle Scholar
  162. Utsinger PD, Resnick D, Zvaifler NJ (1975) Wrist arthropathy in calcium pyrophosphate dihydrate deposition disease. Arthritis Rheum 18(5):485–491PubMedCrossRefGoogle Scholar
  163. van der Heijde DM (1996) Plain X-rays in rheumatoid arthritis: overview of scoring methods, their reliability and applicability. Baillieres Clin Rheumatol 10(3):435–453PubMedCrossRefGoogle Scholar
  164. van der Heijde D, Bellamy N, Calin A et al (1997) Preliminary core sets for endpoints in ankylosing spondylitis. Assessments in Ankylosing Spondylitis Working Group. J Rheumatol 24(11):2225–2229PubMedGoogle Scholar
  165. van der Linden S, Valkenburg H, Cats A (1983) The risk of developing ankylosing spondylitis in HLA-B27 positive individuals: a family and population study. Br J Rheumatol 22(4 Suppl 2):18–19PubMedCrossRefGoogle Scholar
  166. van der Linden S, Valkenburg HA, Cats A (1984) Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum 27(4):361–368PubMedCrossRefGoogle Scholar
  167. Vasanth LC, Foo LF, Potter HG et al (2010) Using magnetic resonance angiography to measure abnormal synovial blood vessels in early inflammatory arthritis: a new imaging biomarker? J Rheumatol 37(6):1129–1135PubMedCrossRefGoogle Scholar
  168. Vyhnanek L, Lavicka J, Blahos J (1960) Roentgenological findings in gout. Radiol Clin (Basel) 29:257Google Scholar
  169. Wachsmuth L, Engelke K (2004) High-resolution ­imaging of osteoarthritis using microcomputed tomography. Methods Mol Med 101:231–248PubMedGoogle Scholar
  170. Wakefield RJ, Gibbon WW, Conaghan PG et al (2000) The value of sonography in the detection of bone erosions in patients with rheumatoid arthritis: a comparison with conventional radiography. Arthritis Rheum 43(12):2762–2770PubMedCrossRefGoogle Scholar
  171. Wakefield RJ, Kong KO, Conaghan PG et al (2003) The role of ultrasonography and magnetic resonance imaging in early rheumatoid arthritis. Clin Exp Rheumatol 21(5 Suppl 31):S42–S49PubMedGoogle Scholar
  172. Wakefield RJ, Conaghan PG, Jarrett S et al (2004) Noninvasive techniques for assessing skeletal changes in inflammatory arthritis: imaging technique. Curr Opin Rheumatol 16(4):435–442PubMedCrossRefGoogle Scholar
  173. Wakefield RJ, D’Agostino MA, Iagnocco A et al (2007a) The OMERACT Ultrasound Group: status of current activities and research directions. J Rheumatol 34(4):848–851PubMedGoogle Scholar
  174. Wakefield RJ, O’Connor PJ, Conaghan PG et al (2007b) Finger tendon disease in untreated early rheumatoid arthritis: a comparison of ultrasound and mag­netic resonance imaging. Arthritis Rheum 57(7):1158–1164PubMedCrossRefGoogle Scholar
  175. Walch G, Boulahia A, Boileau P et al (1998) Primary glenohumeral osteoarthritis: clinical and radiographic classification. The Aequalis Group. Acta Orthop Belg 64(Suppl):246–252Google Scholar
  176. Wang YF, Teng MM, Chang CY et al (2005) Imaging manifestations of spinal fractures in ankylosing spondylitis. AJNR Am J Neuroradiol 26(8):2067–2076PubMedGoogle Scholar
  177. Winn RS, Melhorn JM, De Smet AA (1981) Layering of calcifications in synovial effusions. J Can Assoc Radiol 32(1):66–68PubMedGoogle Scholar
  178. Wolfe F, Hawley DJ (1998) The long-term outcomes of rheumatoid arthritis: work disability: a prospective 18 year study of 823 patients. J Rheumatol 25(11):2108–2117PubMedGoogle Scholar
  179. Wright J (1966) Unusual manifestations of gout. Australas Radiol 10:365PubMedCrossRefGoogle Scholar
  180. Yazici H, Turunc M, Ozdogan H et al (1987) Observer variation in grading sacroiliac radiographs might be a cause of ‘sacroiliitis’ reported in certain disease states. Ann Rheum Dis 46(2):139–145PubMedCrossRefGoogle Scholar
  181. Younes M, Belghali S, Kriaa S et al (2009) Compared imaging of the rheumatoid cervical spine: prevalence study and associated factors. Joint Bone Spine 76(4):361–368PubMedCrossRefGoogle Scholar
  182. Zhang Y, Lewis C, Torner J et al (2007) Reversible MRI features and knee pain fluctuation: the MOST study [abstract]. Osteoarthritis Cartilage 15(suppl):17CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Hans Van der Wall
    • 1
  • Robert Loneragan
    • 2
  • Louise Wong
    • 1
  • Les Barnsley
    • 3
  • Siri Kannangara
    • 3
  1. 1.Concord Nuclear ImagingSydneyAustralia
  2. 2.Department of RadiologyConcord Hospital and University of SydneySydneyAustralia
  3. 3.Department of RheumatologyConcord Hospital and University of SydneySydneyAustralia

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