GIMIAS: An Open Source Framework for Efficient Development of Research Tools and Clinical Prototypes
GIMIAS is a workflow-oriented environment for addressing advanced biomedical image computing and build personalized computational models, which is extensible through the development of application-specific plug-ins. In addition, GIMIAS provides an open source framework for efficient development of research and clinical software prototypes integrating contributions from the Virtual Physiological Human community while allowing business-friendly technology transfer and commercial product development. This framework has been fully developed in ANSI-C++ on top of well known open source libraries like VTK, ITK and wxWidgets among others. Based on GIMIAS, in this paper is presented a workflow for medical image analysis and simulation of the heart.
KeywordsBiomedical imaging cardiovascular modeling Virtual Physiological Human personalized simulations open source software
Unable to display preview. Download preview PDF.
- 2.Hunter, P., Borg, T.: Integration from Proteins to Organs: The Physiome Project. Nature 4(3), 237–243 (2003)Google Scholar
- 3.Fenner, J., Brook, B., Clapworthy, G., Coveney, P., Feipel, V., Gregersen, H., Hose, D., Kohl, P., Lawford, P., McCormack, K., Pinney, D., Thomas, S., Jan, S.V.S., Waters, S., Viceconti, M.: The EuroPhysiome, STEP and a roadmap for the virtual physiological human 366, 2979–2999 (2008)Google Scholar
- 4.Wolf, I., Vetter, M., Wegner, I., Böttger, T., Nolden, M., Schöbinger, M., Hastenteufel, M., Meinzer, H.P.: The Medical Imaging Tookit 9, 594–604 (2005)Google Scholar
- 5.Ordas, S., Oubel, E., Leta, R., Carrera, F., Frangi, A.: A statistical shape model of the heart and its application to model-based segmentation. In: Proc. SPIE Medical Imaging, San Diego, CA, USA, vol. 6511 (2007)Google Scholar
- 6.Streeter, D.: Handbook of Physiology, Section 2: The Cardiovascular System. In: Gross morphology and fiber geometry of the heart. The Heart, ch. 4, vol. I, pp. 61–112. American Physiological Society (1979)Google Scholar