Pediatric and Neonatal Mechanical Ventilation pp 981-997 | Cite as
Post-extubation Stridor
Abstract
While endotracheal intubation is often necessary to facilitate mechanical ventilation for critically ill children, it has been associated with the development of upper airway obstruction upon extubation (Koka et al. 1977; Stoelting and Procter 1968; Pender 1954). With the evolution of intubation, sedation, and mechanical ventilation practices in pediatric intensive care units, the overall incidence of severe post-extubation stridor has decreased, and long-term complications from endotracheal intubation such as subglottic stenosis (Strong and Passy 1977; Markham et al. 1967; Abbott 1968) are now infrequent. Nonetheless, post-extubation stridor results in short-term morbidity with increased length of mechanical ventilation and intensive care unit (ICU) length of stay (Kurachek et al. 2003).
Keywords
Airway Obstruction Endotracheal Tube Pediatric Intensive Care Unit Endotracheal Intubation Noninvasive Positive Pressure VentilationReferences
- Abbott TR (1968) Complications of prolonged nasotracheal intubation in children. Br J Anaesth 40(5):347–353PubMedCrossRefGoogle Scholar
- Adderley RJ, Mullins GC (1987) When to extubate the croup patient: the “leak” test. Can J Anaesth 34(3(Pt 1)):304–306PubMedCrossRefGoogle Scholar
- Anene O, Meert KL, Uy H, Simpson P, Sarnaik AP (1996) Dexamethasone for the prevention of postextubation airway obstruction: a prospective, randomized, double-blind, placebo-controlled trial [see comment]. Crit Care Med 24(10):1666–1669PubMedCrossRefGoogle Scholar
- Arens R, McDonough JM, Corbin AM, Hernandez ME, Maislin G, Schwab RJ, Pack AI (2002) Linear dimensions of the upper airway structure during development: assessment by magnetic resonance imaging. Am J Respir Crit Care Med 165(1):117–122PubMedCrossRefGoogle Scholar
- Argent AC, Newth CJ, Klein M, Argent AC, Newth CJL, Klein M (2008a) The mechanics of breathing in children with acute severe croup. Intensive Care Med 34(2):324–332PubMedCrossRefGoogle Scholar
- Argent AC, Hatherill M, Newth CJ, Klein M, Newth CJL (2008b) The effect of epinephrine by nebulization on measures of airway obstruction in patients with acute severe croup. Intensive Care Med 34(1):138–147PubMedCrossRefGoogle Scholar
- Bates JH, Schmalisch G, Filbrun D, Stocks J (2000) Tidal breath analysis for infant pulmonary function testing. ERS/ATS Task Force on Standards for Infant Respiratory Function Testing. European Respiratory Society/American Thoracic Society. Eur Respir J 16(6):1180–1192PubMedCrossRefGoogle Scholar
- Benditt JO (2005) Esophageal and gastric pressure measurements. Respir Care 50(1):68–75; discussion 75–77PubMedGoogle Scholar
- Bishop MJ, Hibbard AJ, Fink BR, Vogel AM, Weymuller EA Jr (1985) Laryngeal injury in a dog model of prolonged endotracheal intubation. Anesthesiology 62(6):770–773PubMedCrossRefGoogle Scholar
- Blaustein AS, Risser TA, Weiss JW, Parker JA, Holman BL, McFadden ER (1986) Mechanisms of pulsus paradoxus during resistive respiratory loading and asthma. J Am Coll Cardiol 8(3):529–536 [erratum appears in J Am Coll Cardiol 1986 Nov;8(5):1244]PubMedCrossRefGoogle Scholar
- Byerly FL, Haithcock JA, Buchanan IB, Short KA, Cairns BA (2006) Use of high flow nasal cannula on a pediatric burn patient with inhalation injury and post-extubation stridor. Burns 32(1):121–125PubMedCrossRefGoogle Scholar
- Chantarojanasiri T, Preutthipan A, Suwanjutha S (1993) Nasopharyngeal continuous positive airway pressure in postextubation stridor infants. J Med Assoc Thai 76(Suppl 2):169–172PubMedGoogle Scholar
- Cheng KC, Hou CC, Huang HC, Lin SC, Zhang H (2006) Intravenous injection of methylprednisolone reduces the incidence of postextubation stridor in intensive care unit patients [see comment]. Crit Care Med 34(5):1345–1350PubMedCrossRefGoogle Scholar
- Chung Y-H, Chao T-Y, Chiu C-T, Lin M-C (2006) The cuff-leak test is a simple tool to verify severe laryngeal edema in patients undergoing long-term mechanical ventilation. Crit Care Med 34(2):409–414PubMedCrossRefGoogle Scholar
- Clark JA, Lieh-Lai M, Thomas R, Raghavan K, Sarnaik AP (2004) Comparison of traditional and plethysmographic methods for measuring pulsus paradoxus. Arch Pediatr Adolesc Med 158(1):48–51PubMedCrossRefGoogle Scholar
- Cole F (1957) Pediatric formulas for the anesthesiologist. AMA J Dis Child 94(6):672–673PubMedGoogle Scholar
- Collett PW, Perry C, Engel LA (1985) Pressure–time product, flow, and oxygen cost of resistive breathing in humans. J Appl Physiol 58(4):1263–1272PubMedGoogle Scholar
- Courtney SE, Weber KR, Siervogel RM, Spohn WA, Guo S, Malin SW, Bender CV (1992) Effects of dexamethasone on pulmonary function following extubation. J Perinatol 12(3):246–251PubMedGoogle Scholar
- Couser RJ, Ferrara TB, Falde B, Johnson K, Schilling CG, Hoekstra RE (1992) Effectiveness of dexamethasone in preventing extubation failure in preterm infants at increased risk for airway edema. J Pediatr 121(4):591–596PubMedCrossRefGoogle Scholar
- Davies MW, Davis PG (2002) Nebulized racemic epinephrine for extubation of newborn infants. Cochrane Database Syst Rev (1):CD000506 [update of Cochrane Database Syst Rev. 2000;(2):CD000506; PMID: 10796376]Google Scholar
- Davis GM, Cooper DM, Mitchell I (1993) The measurement of thoraco-abdominal asynchrony in infants with severe laryngotracheobronchitis. Chest 103(6):1842–1848PubMedCrossRefGoogle Scholar
- De Bast Y, De Backer D, Moraine J-J, Lemaire M, Vandenborght C, Vincent J-L (2002) The cuff leak test to predict failure of tracheal extubation for laryngeal edema. Intensive Care Med 28(9):1267–1272PubMedCrossRefGoogle Scholar
- Deakers TW, Reynolds G, Stretton M, Newth CJ (1994) Cuffed endotracheal tubes in pediatric intensive care. J Pediatr 125(1):57–62PubMedCrossRefGoogle Scholar
- Edmunds S, Weiss I, Harrison R (2001) Extubation failure in a large pediatric ICU population. Chest 119(3):897–900PubMedCrossRefGoogle Scholar
- Ferrara TB, Georgieff MK, Ebert J, Fisher JB (1989) Routine use of dexamethasone for the prevention of postextubation respiratory distress. J Perinatol 9(3):287–290PubMedGoogle Scholar
- Fine GF, Borland LM (2004) The future of the cuffed endotracheal tube. Paediatr Anaesth 14(1):38–42PubMedCrossRefGoogle Scholar
- Finholt DA, Henry DB, Raphaely RC (1985) Factors affecting leak around tracheal tubes in children. Can Anaesth Soc J 32(4):326–329PubMedCrossRefGoogle Scholar
- Foland JA, Super DM, Dahdah NS, Mhanna MJ (2002) The use of the air leak test and corticosteroids in intubated children: a survey of pediatric critical care fellowship directors. Respir Care 47(6):662–666PubMedGoogle Scholar
- Francois B, Bellissant E, Gissot V, Desachy A, Normand S, Boulain T, Brenet O, Preux PM, Vignon P (2007) Association des Reanimateurs du C-O: 12-h pretreatment with methylprednisolone versus placebo for prevention of postextubation laryngeal oedema: a randomised double-blind trial. Lancet 369(9567):1083–1089PubMedCrossRefGoogle Scholar
- Frey B, Freezer N (2001) Diagnostic value and pathophysiologic basis of pulsus paradoxus in infants and children with respiratory disease. Pediatr Pulmonol 31(2):138–143PubMedCrossRefGoogle Scholar
- Fujioka M, Young LW, Girdany BR (1979) Radiographic evaluation of adenoidal size in children: adenoidal-nasopharyngeal ratio. AJR Am J Roentgenol 133(3):401–404PubMedCrossRefGoogle Scholar
- Gomes Cordeiro AM, Fernandes JC, Troster EJ (2004) Possible risk factors associated with moderate or severe airway injuries in children who underwent endotracheal intubation. Pediatr Crit Care Med 5(4):364–368PubMedCrossRefGoogle Scholar
- Graham AS, Chandrashekharaiah G, Citak A, Wetzel RC, Newth CJL (2007) Positive end-expiratory pressure and pressure support in peripheral airways obstruction: work of breathing in intubated children. Intensive Care Med 33(1):120–127Google Scholar
- Grundfast KM, Camilon FS Jr, Pransky S, Barber CS, Fink R (1990) Prospective study of subglottic stenosis in intubated neonates. Ann Otol Rhinol Laryngol 99(5 Pt 1):390–395PubMedCrossRefGoogle Scholar
- Hammer J, Newth CJ, Deakers TW (1995) Validation of the phase angle technique as an objective measure of upper airway obstruction. Pediatr Pulmonol 19(3):167–173PubMedCrossRefGoogle Scholar
- Harel Y, Vardi A, Quigley R, Brink LW, Manning SC, Carmody TJ, Levin DL (1997) Extubation failure due to post-extubation stridor is better correlated with neurologic impairment than with upper airway lesions in critically ill pediatric patients. Int J Pediatr Otorhinolaryngol 39(2):147–158PubMedCrossRefGoogle Scholar
- Harrison GA, Tonkin JP (1965) Laryngeal complications of prolonged endotracheal intubation. Med J Aust 2(17):709–710PubMedGoogle Scholar
- Harrison GA, Tonkin JP (1967) Some serious laryngeal complications of prolonged endotracheal intubation. Med J Aust 1(12):605–606PubMedGoogle Scholar
- Hartley M, Vaughan RS (1993) Problems associated with tracheal extubation [see comment]. Br J Anaesth 71(4):561–568PubMedCrossRefGoogle Scholar
- Ho LI, Harn HJ, Lien TC, Hu PY, Wang JH (1996) Postextubation laryngeal edema in adults. Risk factor evaluation and prevention by hydrocortisone. Intensive Care Med 22(9):933–936PubMedCrossRefGoogle Scholar
- Isono S, Tanaka A, Ishikawa T, Nishino T (2000) Developmental changes in collapsibility of the passive pharynx during infancy. Am J Respir Crit Care Med 162(3 Pt 1):832–836PubMedCrossRefGoogle Scholar
- Ito H, Sobue K, So M-H, Sugiura T, Sasano H, Takeuchi A, Katsuya H (2006) Postextubation airway management with nasal continuous positive airway pressure in a child with Down syndrome. J Anesth 20(2):106–108PubMedCrossRefGoogle Scholar
- Jaber S, Chanques G, Matecki S, Ramonatxo M, Vergne C, Souche B, Perrigault P-F, Eledjam J-J (2003) Post-extubation stridor in intensive care unit patients. Risk factors evaluation and importance of the cuff-leak test. Intensive Care Med 29(1):69–74PubMedGoogle Scholar
- Kaye G (1936) Sequelae of anaesthesia. Br J Anaesth 13:157–176CrossRefGoogle Scholar
- Kemper KJ, Benson MS, Bishop MJ (1991a) Predictors of postextubation stridor in pediatric trauma patients. Crit Care Med 19(3):352–355PubMedCrossRefGoogle Scholar
- Kemper KJ, Ritz RH, Benson MS, Bishop MS (1991b) Helium-oxygen mixture in the treatment of postextubation stridor in pediatric trauma patients. Crit Care Med 19(3):356–359PubMedCrossRefGoogle Scholar
- Khemani R, Bart R, Newth C (2007) Respiratory monitoring during mechanical ventilation. Paediatr Child Health 17(5):193–201CrossRefGoogle Scholar
- Khemani R, Randolph A, Markovitz B (2009) Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults. Cochrane Database Syst Rev (3) CD001000; UI:19588321 PMID 19588321Google Scholar
- Khine HH, Corddry DH, Kettrick RG, Martin TM, McCloskey JJ, Rose JB, Theroux MC, Zagnoev M (1997) Comparison of cuffed and uncuffed endotracheal tubes in young children during general anesthesia. Anesthesiology 86(3):627–631; discussion 627APubMedCrossRefGoogle Scholar
- Klein M, Reynolds LG (1986) Relief of sleep-related oropharyngeal airway obstruction by continuous insufflation of the pharynx. Lancet 1(8487):935–939PubMedCrossRefGoogle Scholar
- Koka BV, Jeon IS, Andre JM, MacKay I, Smith RM (1977) Postintubation croup in children. Anesth Analg 56(4):501–505PubMedCrossRefGoogle Scholar
- Kriner EJ, Shafazand S, Colice GL (2005) The endotracheal tube cuff-leak test as a predictor for postextubation stridor [see comment]. Respir Care 50(12):1632–1638PubMedGoogle Scholar
- Kurachek SC, Newth CJ, Quasney MW, Rice T, Sachdeva RC, Patel NR, Takano J, Easterling L, Scanlon M, Musa N et al (2003) Extubation failure in pediatric intensive care: a multiple-center study of risk factors and outcomes. Crit Care Med 31(11):2657–2664 [erratum appears in Crit Care Med. Jul;32(7):1632–3 Note: Scanlon Mathew [corrected to Scanlon Matthew]]PubMedCrossRefGoogle Scholar
- Kuusela AL, Vesikari T (1988) A randomized double-blind, placebo-controlled trial of dexamethasone and racemic epinephrine in the treatment of croup. Acta Paediatr Scand 77(1):99–104PubMedCrossRefGoogle Scholar
- Lee C-H, Peng M-J, Wu C-L (2007) Dexamethasone to prevent postextubation airway obstruction in adults: a prospective, randomized, double-blind, placebo-controlled study [see comment]. Crit Care 11(4):R72PubMedCentralPubMedCrossRefGoogle Scholar
- Lin C-D, Cheng Y-K, Chang J-S, Lin H-J, Su B-H, Tsai M-H (2002) Endoscopic survey of post-extubation stridor in children. Acta Paediatr Taiwan 43(2):91–95PubMedGoogle Scholar
- Markham WG, Blackwood MJ, Conn AW (1967) Prolonged nasotracheal intubation in infants and children. Can Anaesth Soc J 14(1):11–21PubMedCrossRefGoogle Scholar
- Markovitz BP, Randolph AG, Khemani RG (2008) Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults. Cochrane Database Syst Rev (2):CD001000 [update of Cochrane Database Syst Rev. 2000;(2):CD001000; PMID: 10796576]Google Scholar
- Martins RHG, Dias NH, Castilho EC, Trindade SHK (2006) Endoscopic findings in children with stridor. Braz J Otorhinolaryngol 72(5):649–653PubMedGoogle Scholar
- McCarthy K (1940) Endotracheal nitrous oxide anesthesia for tonsillectomy; report of 1,500 cases. Anesthesiology 1:216–222CrossRefGoogle Scholar
- Mhanna MJ, Zamel YB, Tichy CM, Super DM (2002) The “air leak” test around the endotracheal tube, as a predictor of postextubation stridor, is age dependent in children. Crit Care Med 30(12):2639–2643PubMedCrossRefGoogle Scholar
- Miller RL, Cole RP (1996) Association between reduced cuff leak volume and postextubation stridor. Chest 110(4):1035–1040PubMedCrossRefGoogle Scholar
- Newth CJ, Levison H, Bryan AC (1972) The respiratory status of children with croup. J Pediatr 81(6):1068–1073PubMedCrossRefGoogle Scholar
- Newth CJ, Rachman B, Patel N, Hammer J (2004) The use of cuffed versus uncuffed endotracheal tubes in pediatric intensive care. J Pediatr 144(3):333–337PubMedCrossRefGoogle Scholar
- Obrien K, Newth C, Leung K, Coates A (2007) Epinephrine delivery using a humidified high flow oxygen vaporizer system. In: American Thoracic Society: 2007, San Francisco. American Journal of Respiratory and Critical Care Medicine. A195Google Scholar
- Ochoa ME, Marin MC, Frutos-Vivar F, Gordo F, Latour-Perez J, Calvo E, Esteban A (2009) Cuff-leak test for the diagnosis of upper airway obstruction in adults: a systematic review and meta-analysis. Intensive Care Med 35:1171–1179PubMedCrossRefGoogle Scholar
- Pender JW (1954) Endotracheal anesthesia in children: advantages and disadvantages. Anesthesiology 15(5):495–506PubMedCrossRefGoogle Scholar
- Prisk GK, Hammer J, Newth CJL (2002) Techniques for measurement of thoracoabdominal asynchrony. Pediatr Pulmonol 34(6):462–472PubMedCrossRefGoogle Scholar
- Puhakka HJ, Kero P, Valli P, Iisalo E, Erkinjuntti M (1990) Subglottic stenosis in neonates and children. Clinical findings and therapy. Acta Paediatr Scand 79(4):397–401PubMedCrossRefGoogle Scholar
- Rodeberg DA, Easter AJ, Washam MA, Housinger TA, Greenhalgh DG, Warden GD (1995) Use of a helium-oxygen mixture in the treatment of postextubation stridor in pediatric patients with burns. J Burn Care Rehabil 16(5):476–480PubMedCrossRefGoogle Scholar
- Schwartz RE, Stayer SA, Pasquariello CA (1993) Tracheal tube leak test–is there inter-observer agreement? [see comment]. Can J Anaesth 40(11):1049–1052PubMedCrossRefGoogle Scholar
- Shiomi T, Guilleminault C, Stoohs R, Schnittger I (1991) Leftward shift of the interventricular septum and pulsus paradoxus in obstructive sleep apnea syndrome. Chest 100(4):894–902PubMedCrossRefGoogle Scholar
- Sivan Y, Deakers TW, Newth CJ (1990) Thoracoabdominal asynchrony in acute upper airway obstruction in small children. Am Rev Respir Dis 142(3):540–544PubMedCrossRefGoogle Scholar
- Steele DW, Santucci KA, Wright RO, Natarajan R, McQuillen KK, Jay GD (1998) Pulsus paradoxus: an objective measure of severity in croup. Am J Respir Crit Care Med 157(1):331–334PubMedCrossRefGoogle Scholar
- Stoelting RK, Procter J (1968) Acute laryngeal obstruction after endotracheal anesthesia. JAMA 206(7):1558–1559PubMedCrossRefGoogle Scholar
- Strong RM, Passy V (1977) Endotracheal intubation. Complications in neonates. Arch Otolaryngol 103(6):329–335PubMedCrossRefGoogle Scholar
- Sundaram RK, Nikolic G (1996) Successful treatment of post-extubation stridor by continuous positive airway pressure. Anaesth Intensive Care 24(3):392–393PubMedGoogle Scholar
- Swami A, Spodick DH (2003) Pulsus paradoxus in cardiac tamponade: a pathophysiologic continuum. Clin Cardiol 26(5):215–217PubMedCrossRefGoogle Scholar
- Tamburro RF, Ring JC, Womback K (2002) Detection of pulsus paradoxus associated with large pericardial effusions in pediatric patients by analysis of the pulse-oximetry waveform. Pediatrics 109(4):673–677PubMedCrossRefGoogle Scholar
- Tellez DW, Galvis AG, Storgion SA, Amer HN, Hoseyni M, Deakers TW (1991) Dexamethasone in the prevention of postextubation stridor in children. J Pediatr 118(2):289–294PubMedCrossRefGoogle Scholar
- Thompson A (2006) Pediatric airway management. In: Zimmerman J, Furhman B (eds) Pediatric critical care, 3rd edn. Mosby, Philadelphia, pp 492–493Google Scholar
- Tibballs J, Shann FA, Landau LI (1992) Placebo-controlled trial of prednisolone in children intubated for croup. Lancet 340(8822):745–748PubMedCrossRefGoogle Scholar
- Waisman Y, Klein BL, Boenning DA, Young GM, Chamberlain JM, O’Donnell R, Ochsenschlager DW (1992) Prospective randomized double-blind study comparing L-epinephrine and racemic epinephrine aerosols in the treatment of laryngotracheitis (croup). Pediatrics 89(2):302–306PubMedGoogle Scholar
- Wang CH, Lin HC, Huang TJ, Yang CT, Yu CT, Kuo HP (1996) Differential effects of nasal continuous positive airway pressure on reversible or fixed upper and lower airway obstruction. Eur Respir J 9(5):952–959PubMedCrossRefGoogle Scholar
- Weber JE, Chudnofsky CR, Younger JG, Larkin GL, Boczar M, Wilkerson MD, Zuriekat GY, Nolan B, Eicke DM (2001) A randomized comparison of helium-oxygen mixture (Heliox) and racemic epinephrine for the treatment of moderate to severe croup [see comment]. Pediatrics 107(6):E96PubMedCrossRefGoogle Scholar
- Weiner DJ, Allen JL, Panitch HB (2003) Infant pulmonary function testing. Curr Opin Pediatr 15(3):316–322PubMedCrossRefGoogle Scholar
- Wesley AG, Bruce R, Holloway R (1968) Arterial blood gases as a guide to management of infective croup. S Afr Med J 42(45):1237–1239PubMedGoogle Scholar
- Westley CR, Cotton EK, Brooks JG (1978) Nebulized racemic epinephrine by IPPB for the treatment of croup: a double-blind study. Am J Dis Child 132(5):484–487PubMedCrossRefGoogle Scholar
- Wheeler M, Roth AG, Dunham ME, Rae B, Cote CJ (1998) A bronchoscopic, computer-assisted examination of the changes in dimension of the infant tracheal lumen with changes in head position: implications for emergency airway management. Anesthesiology 88(5):1183–1187PubMedCrossRefGoogle Scholar
- Wiel E, Vilette B, Darras JA, Scherpereel P, Leclerc F (1997) Laryngotracheal stenosis in children after intubation. Report of five cases. Paediatr Anaesth 7(5):415–419PubMedCrossRefGoogle Scholar
- Willis BC, Graham AS, Yoon E, Wetzel RC, Newth CJL (2005) Pressure-rate products and phase angles in children on minimal support ventilation and after extubation. Intensive Care Med 31(12):1700–1705PubMedCrossRefGoogle Scholar
- Wong FWH (2007) Pulsus paradoxus in ventilated and non-ventilated patients. Dynamics 18(3):16–18PubMedGoogle Scholar
- Wratney AT, Benjamin DK Jr, Slonim AD, He J, Hamel DS, Cheifetz IM (2008) The endotracheal tube air leak test does not predict extubation outcome in critically ill pediatric patients. Pediatr Crit Care Med 9(5):490–496PubMedCentralPubMedCrossRefGoogle Scholar
- Yalamanchili K, Summer W, Valentine V (2005) Pectus excavatum with inspiratory inferior vena cava compression: a new presentation of pulsus paradoxus. Am J Med Sci 329(1):45–47PubMedCrossRefGoogle Scholar