Genotype and Haplotype Reconstruction from Low-Coverage Short Sequencing Reads
Recent advances in high-throughput sequencing (HTS) technologies have led to orders of magnitude higher throughput compared to classic Sanger sequencing (see  for a review). Coupled with continuously decreasing sequencing costs, HTS data provides opportunities to study genome structure, function, and evolution at an unprecedented scale, and is profoundly transforming biomedical research.
KeywordsHaplotype Sequence Paternal Chromosome Haplotype Reconstruction Unprecedented Scale Common Human Disease
- 1.1000 Genomes Project Consortium, http://www.1000genomes.org/