Fast, Accurate and Precise Mid-Sagittal Plane Location in 3D MR Images of the Brain

  • Felipe P. G. Bergo
  • Alexandre X. Falcão
  • Clarissa L. Yasuda
  • Guilherme C. S. Ruppert
Part of the Communications in Computer and Information Science book series (CCIS, volume 25)


Extraction of the mid-sagittal plane (MSP) is a key step for brain image registration and asymmetry analysis. We present a fast MSP extraction method for 3D MR images, based on automatic segmentation of the brain and on heuristic maximization of the cerebro-spinal fluid within the MSP. The method is robust to severe anatomical asymmetries between the hemispheres, caused by surgical procedures and lesions. The method is also accurate with respect to MSP delineations done by a specialist. The method was evaluated on 64 MR images (36 pathological, 20 healthy, 8 synthetic), and it found a precise and accurate approximation of the MSP in all of them with a mean time of 60.0 seconds per image, mean angular variation within a same image (precision) of 1.26o and mean angular difference from specialist delineations (accuracy) of 1.64o.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2008

Authors and Affiliations

  • Felipe P. G. Bergo
    • 1
  • Alexandre X. Falcão
    • 1
  • Clarissa L. Yasuda
    • 2
  • Guilherme C. S. Ruppert
    • 1
  1. 1.LIV, Institute of ComputingUniversity of Campinas (UNICAMP)CampinasBrazil
  2. 2.Dept. of Neurology, Faculty of Medical SciencesUniversity of Campinas (UNICAMP)CampinasBrazil

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