Towards Virtual Epidemiology: An Agent-Based Approach to the Modeling of H5N1 Propagation and Persistence in North-Vietnam

  • Edouard Amouroux
  • Stéphanie Desvaux
  • Alexis Drogoul
Part of the Lecture Notes in Computer Science book series (LNCS, volume 5357)

Abstract

In this paper we claim that a combination of an agent-based model and a SIG-based environmental model can act as a “virtual laboratory” for epidemiology. Following the needs expressed by epidemiologists studying micro-scale dynamics of avian influenza in Vietnam, and after a review of the epidemiological models proposed so far, we present our model, built on top of the GAMA platform, and explain how it can be adapted to the epidemiologists’ requirements. One notable contribution of this work is to treat the environment, together with the social structure and the animals’ behaviors, as a first-class citizen in the model, allowing epidemiologists to consider heterogeneous micro and macro factors in their exploration of the causes of the epidemic.

Keywords

Multi-Agent Systems Agent-Based Models epidemiological models environmental models GAMA platform 

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References

  1. 1.
    Gilbert, M., Xiao, X., Pfeiffer, D.U., Epprecht, M., Boles, et al.: Mapping H5N1 highly pathogenic avian influenza risk in Southeast Asia. Proc. Natl. Acad. Sci. USA. 105, 4769–4774Google Scholar
  2. 2.
    Dung Nguyen, T., Vinh Nguyen, T., Vijaykrishna, D., Webster, R.G., Guan, Y., Peiris, J.S.M., Smith, G.J.D.: Multiple sublineages of influenza A virus (H5N1), Vietnam, 2005 2007, Emerging Infectious Diseases, 14, 4 (2008)Google Scholar
  3. 3.
    Agrifood consulting international: The Impact of Avian Influenza on Poultry Sector Restructuring and its Socio-economic Effects (2006)Google Scholar
  4. 4.
    Chen, H., Li, Y., Li, Z., Shi, J., Shinya, K., Deng, G., et al.: Properties and dissemination of H5N1 Viruses isolated during an influenza outbreak in migratory waterfowl in Western China. J. of Viro. 80, 5976–5983 (2006)CrossRefGoogle Scholar
  5. 5.
    Ito, T., Okazaki, K., Kawaoka, Y., Takada, A., Webster, R.G., Kida, H.: Perpetuation of influenza A viruses in Alaskan waterfowl reservoirs. Arch. of Viro. 140(7), 1163–1172 (1995)CrossRefGoogle Scholar
  6. 6.
    McKendrick, A.G.: Applications of mathematics to medical problems. Proc. of the Edinburgh Mathematical Society 44, 1–34 (1925)Google Scholar
  7. 7.
    Abbas, K., Mikler, A., Ramezani, A., Meneze, S.: Computational epidemiology: Bayesian disease surveillance. In: Proc. of ICBAm 2004 proceedings (2004)Google Scholar
  8. 8.
    Durand, B., Mahul, O.: An extended state-transition model for foot-and-mouth disease epidemics in France. Preventive Veterinary Medicine 47, 1–2 (2000)CrossRefGoogle Scholar
  9. 9.
    Artzrouni, M., Gouteux, J.P., et al.: Population dynamics of sleeping sickness: A micro simulation. Simulation & Gaming 32(2), 215–227 (2001)CrossRefMATHGoogle Scholar
  10. 10.
    Brouwers, L.: MicroPox: a Large-scale and Spatially Explicit Microsimulation Model for Smallpox Transmission. In: Proc. of the Intl. Conf. of Health Sciences Simulation (2005)Google Scholar
  11. 11.
    Turner, J., Begon, M., Bowers, R.: Modelling pathogen transmission: the interrelationship between local and global approaches. Proc. Biol. Sci. 270(1510), 105–112 (2003)CrossRefGoogle Scholar
  12. 12.
    Ghani, A.: Models for an Outbreak of Avian Influenza in the UK Poultry Flock, Journées de modélisation en épidémiologie animale du CIRAD (2007)Google Scholar
  13. 13.
    Wilensky, U.: NetLogo Virus model (1998), http://ccl.northwestern.edu/netlogo/models/Virus
  14. 14.
    Muller, G., Grébaut, P., Gouteux, J.P.: An agent-based model of sleeping sickness: simulation trials of a forest focus in southern Cameroon, Éd. Sc. et Méd. Elsevier, Amsterdam (2004)Google Scholar
  15. 15.
    Badariotti, D., Banos, A., Laperrière, V.: Vers une approche individu-centrée pour modéliser et simuler l’expression spatiale d’une maladie transmissible: la peste à Madagascar, cybergeo (2007), http://www.cybergeo.eu/index9052.html
  16. 16.
    Bénédicte, S.J.: Atlas Bac Hung Hai, Gret (personnal communication) (1999)Google Scholar
  17. 17.
    Desvaux, S., Vu, D.-T.: A general review and description of the poultry production in Vietnam. Agricultural publishing house (2008)Google Scholar
  18. 18.
    Amouroux, E., Chu, T.Q., Boucher, A., Drogoul, A.: GAMA: an environment for implementing and running spatially explicit multi-agent simulations. LNCS (LNAI). Springer, Heidelberg (2007)Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2008

Authors and Affiliations

  • Edouard Amouroux
    • 1
    • 2
  • Stéphanie Desvaux
    • 3
    • 4
  • Alexis Drogoul
    • 1
    • 2
  1. 1.IRD UR079 GEODESBondyFrance
  2. 2.Equipe MSI, IFIHa NoiViet Nam
  3. 3.CIRAD, Campus International de BaillarguetMontpellierFrance
  4. 4.PRISE Consortium in Vietnam c/° NIVRHa NoiViet Nam

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