Detection of Obstructive Sleep Apnea by Empirical Mode Decomposition on Tachogram

  • Bogdan Mijović
  • J. Corthout
  • S. Vandeput
  • M. Mendez
  • S. Cerutti
  • S. Van Huffel
Part of the IFMBE Proceedings book series (IFMBE, volume 22)

Abstract

In this study we proposed a method for screening the obstructive apnea in an easy and non-invasive way by following the tachogram. Ensemble Empirical Mode Decomposition (EEMD), as proposed in [6] is applied, Intrinsic Mode Functions (IMF) are derived and amplitudes and frequencies from different modes are extracted. Frequencies are computed by applying a new Generalized Zero Crossing method on IMF as proposed by Huang [7]. Once frequencies and amplitudes of different modes have been extracted, the optimal performing subset of features has been derived. Linear discriminant analysis (LDA) was used to classify apneic events on a minute-by-minute basis. Our algorithm showed fairly good performance with sensitivity of nearly 89% and accuracy higher than 83% which is at least comparable with the best performing methods. However, the set of features used in this work was significantly smaller than in other studies, e.g. Corthout et al. [5]. In this study only EMD-based methods are used in order to show the power of that family of algorithms, and only the tachogram is processed, so the computational power of the algorithm is enhanced.

Keywords

Empirical Mode Decomposition Obstructive Sleep Apnea Heart Rate Variability Automatic Detection 

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References

  1. 1.
    Morgenthaler T I, Kagramanov V, Hanak V, and Decker P A (2006) Complex sleep apnea syndrome: Is it a unique clinical syndrome? Sleep 29(9):1203–1209Google Scholar
  2. 2.
    Young T, Palta M, Dempsey J, Skatrud J, Weber S, and Badr S (1993) The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328:1230–1235.CrossRefGoogle Scholar
  3. 3.
    Kodkrnvuo M, Kaprio J, Telakivi T, Partinen M, Heikkila K, Sarna S (1987) Snoring as a risk factor for ischemic heart disease and stroke in men. Br Med J 294:16–19CrossRefGoogle Scholar
  4. 4.
    He J, Kryger M H, Zorick F J, Conway W, Roth T (1988) Mortality and apnea index in obstructive sleep apnea. Expirience in 385 male patients. Chest 1:9–14CrossRefGoogle Scholar
  5. 5.
    Corthout J, Mendez M O, Bianchi A M, Penzel T, Van Huffel S, Cerutti S (2008) Automatic screening of Obstructive Sleep Apnea from the ECG based on Empirical Mode Decomposition and Wavelet Analysis. EMBC Proc. vol. 30, International Conference of the IEEE Eng. in Med. and Biol. Soc., Vancouver, Canada, 2008, 4 pgGoogle Scholar
  6. 6.
    Zhaohua W, Huang N E (2005) Ensemble empirical mode decomposition: A noise assisted data analysis method. Centre for Ocean-Land-Atmosphere Studies, Tech Rep 193.Google Scholar
  7. 7.
    Huang N E, (2006) Computing frequency by using generalized zero-crossing applied to intrinsic mode functions. US Patent 6990436Google Scholar
  8. 8.
    Mateo J, Laguna P (2003) Analysis of heart rate variability in the presence of ectopic beats using the heart timing signal. IEEE Trans on Biomed Eng 50(3):334–343CrossRefGoogle Scholar
  9. 9.
    Penzel T, Moody G B, Mark R G, Goldberger A L, Peter J H (2000) The apnea-ECG database. Computers in Cardiology 2000 255–258 DOI 10.1109/CIC.2000.898505.Google Scholar
  10. 10.
    Huang N E, Shen Z, Long H R, Wu M C, Shih H H, Zheng Q, Yen N C, Thung C C, Liu H H (1998) The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis, Proc R Soc London 454:903–995MATHCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2009

Authors and Affiliations

  • Bogdan Mijović
    • 1
  • J. Corthout
    • 1
  • S. Vandeput
    • 1
  • M. Mendez
    • 2
  • S. Cerutti
    • 2
  • S. Van Huffel
    • 1
  1. 1.Dept. Of Electrical Engineering — ESAT/SCDKatholieke Universiteit LeuvenLeuvenBelgium
  2. 2.Dept. of Biomedical EngineeringPolitecnico di MilanoMilanoItaly

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