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Resonant Spike Propagation in Coupled Neurons with Subthreshold Activity

  • Belén Sancristóbal
  • José M. Sancho
  • Jordi García-Ojalvo
Part of the Lecture Notes in Computer Science book series (LNCS, volume 5164)

Abstract

Chemical coupling between neurons is only active when the pre-synaptic neuron is firing, and thus it does not allow for the propagation of subthreshold activity. Electrical coupling via gap junctions, on the other hand, is also ubiquitous and, due to its diffusive nature, transmits both subthreshold and suprathreshold activity between neurons. We study theoretically the propagation of spikes between two neurons that exhibit strong subthreshold oscillations, and which are coupled via both chemical synapses and gap junctions. Due to the electrical coupling, the periodic subthreshold activity is synchronized in the two neurons, and affects propagation of spikes in such a way that for certain values of the delay in the synaptic coupling, propagation is not possible. This effect could provide a mechanism for the modulation of information transmission in neuronal networks.

Keywords

Electrical Coupling Spike Propagation Chemical Coupling Chemical Synapse Couple Neuron 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2008

Authors and Affiliations

  • Belén Sancristóbal
    • 1
  • José M. Sancho
    • 2
  • Jordi García-Ojalvo
    • 1
  1. 1.Departament de Física i Enginyeria NuclearUniversitat Politècnica de CatalunyaTerrassaSpain
  2. 2.Departament d’Estructura i Constituents de la MatèriaUniversitat de BarcelonaBarcelonaSpain

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