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Short Term Plasticity Provides Temporal Filtering at Chemical Synapses

  • Bruce P. Graham
  • Christian Stricker
Part of the Lecture Notes in Computer Science book series (LNCS, volume 5164)

Abstract

Chemical synapses exhibit a wide range of mechanisms that modulate the postsynaptic response due to presynaptic action potentials (APs) as a function of the arrival pattern of the presynaptic APs. Here we demonstrate that combinations of depression, facilitation and frequency-dependent recovery will give synapses that are either sensitive to the steady-state input signal, or to the onsets and offsets of signal transients. In addition, a synapse may be tuned to preferentially respond to low frequency modulation of an input signal.

Keywords

Synaptic transmission short term plasticity depression facilitation 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2008

Authors and Affiliations

  • Bruce P. Graham
    • 1
  • Christian Stricker
    • 2
  1. 1.Department of Computing Science and MathematicsUniversity of StirlingStirlingU.K.
  2. 2.Division of Neuroscience, JCSMRAustralian National UniversityCanberraAustralia

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