Probabilistic Anatomo-Functional Parcellation of the Cortex: How Many Regions?
Understanding brain structure and function entails the inclusion of anatomical and functional information in a common space, in order to study how these different informations relate to each other in a population of subjects. In this paper, we revisit the parcellation model and explicitly combine anatomical features, i.e. a segmentation of the cortex into gyri, with a functional information under the form of several cortical maps, which are used to further subdivide the gyri into functionally consistent regions. A probabilistic model is introduced, and the parcellation model is estimated using a Variational Bayes approach. The number of regions in the model is validated based on cross-validation. It is found that about 250 patches of cortex can be delineated both in the left and right hemisphere based on this procedure.
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- 9.Devlin, J.T., Poldrack, R.A.: In praise of tedious anatomy. Neuroimage 37, 1033–41; discussion 1050–8 (2007)Google Scholar
- 11.Thyreau, B., Thirion, B., Flandin, G., et al.: Anatomo-functional description of the brain: A probabilistic approach. In: ICASSP, pp. V–V (2006) Google Scholar
- 13.Perrot, M., Rivière, D., Mangin, J.F.: Identifying cortical sulci from localizations, shape and local organization. In: 5th ISBI, Paris, France, pp. 420–423 (2008)Google Scholar