Coupled Meshfree-BEM Platform for Electrocardiographic Simulation: Modeling and Validations

  • Linwei Wang
  • Heye Zhang
  • Ken C. L. Wong
  • Pengcheng Shi
Part of the Lecture Notes in Computer Science book series (LNCS, volume 5128)


The foremost premise for the success of noninvasive volumetric myocardial transmembrane (TMP) imaging from body surface potential (BSP) recordings is a realistic yet efficient electrocardiographic model which relates volumetric myocardial TMP distributions to BSP distributions. With a view towards the inverse problem, appropriate model simplifications should be emphasized to balance the accuracy of the model with the feasibility of the inversion. In this paper, we present a novel coupled meshfree-BEM platform to represent the combined heart-torso structure and derive the associated TMP-to-BSP models. The numerical accuracy and convergency of the presented approach is verified against analytic solutions on a synthetic geometry. The associated simplifications are justified by comparing models at different level of complexity, which further demonstrates the benefits of homogeneous torso assumption in the inverse problem. Initial simulation experiments on a realistic heart-torso structure further show the physiological plausibility of the presented approach.


Inverse Problem Conductivity Tensor Meshfree Method Relative Root Mean Square Error Electrical Anisotropy 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2008

Authors and Affiliations

  • Linwei Wang
    • 1
  • Heye Zhang
    • 2
  • Ken C. L. Wong
    • 1
  • Pengcheng Shi
    • 1
  1. 1.Golisano College of Computing and Information ScienceRochester Institute of Technology, RochesterNew York
  2. 2.Bioengineering InstituteUniversity of AucklandAuckland

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