Evaluation of Malignant Bone Disease Using DW-MRI

  • K. Nakanishi
  • A. Gutzeit
Part of the Medical Radiology book series (MEDRAD)

Summary

The bones are frequently involved as a site of meta-static disease in patients with cancer. Accurate determination of the presence, location and extent of bone involvement is of therapeutic and prognostic importance. Diffusion-weighted MR imaging performed regionally or as whole-body imaging has been shown to have a high diagnostic accuracy for the identification of bone metastases when combined with conventional MR imaging. Both qualitative and quantitative DW-MRI have also been found to be of value for distinguishing between benign and malignant causes of vertebral fractures. There is also promise in the application of quantitative ADC for evaluating treatment response of malignant bone diseases, as current imaging criteria are inadequate in assessing treatment changes of bone lesions to therapy.

Keywords

Bone Metastasis High Signal Intensity Bone Scintigraphy Echo Train Length Stir Imaging 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • K. Nakanishi
    • 1
  • A. Gutzeit
    • 2
  1. 1.Department of Diagnostic RadiologyOsaka Medical Center for Cancer and Cardiovascular DiseasesNakamichi, Higashinari-KuJapan
  2. 2.Department of Diagnostic and Interventional RadiologyKantonsspital WinterthurWinterthurSwitzerland

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