Data Access and Management in ACGT: Tools to Solve Syntactic and Semantic Heterogeneities Between Clinical and Image Databases

  • Luis Martín
  • Erwin Bonsma
  • Alberto Anguita
  • Jeroen Vrijnsen
  • Miguel García-Remesal
  • José Crespo
  • Manolis Tsiknakis
  • Víctor Maojo
Part of the Lecture Notes in Computer Science book series (LNCS, volume 4802)

Abstract

Recent changes in data management within post-genomic clinical trials have emphasized the need for novel methods and tools to solve semantic and syntactic heterogeneities among distributed sources of information. ACGT is an Integrated Project funded by the European Commission that aims at building a GRID-based platform comprised by a set of tools to support multi-centric post-genomic clinical trials on cancer. The main goal of ACGT is to provide seamless access to heterogeneous sources of information. For this purpose, two core tools were developed and included in the ACGT architecture: the ACGT Semantic Mediator (ACGT-SM), and the Data Access Wrappers (ACGT-DAWs). The ACGT-SM addresses semantics and schema integration, while the ACGT-DAWs cope with syntactic heterogeneities. Once the sources are bridged together, they can be seamlessly accessed using the RDQL query language.We tested our tools using a set of three relational and DICOM based image sources obtaining promising results.

Keywords

Database Integration Semantic Mediation Ontologies Clinical Trial Databases DICOM 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2007

Authors and Affiliations

  • Luis Martín
    • 1
  • Erwin Bonsma
    • 2
  • Alberto Anguita
    • 1
  • Jeroen Vrijnsen
    • 2
  • Miguel García-Remesal
    • 1
  • José Crespo
    • 1
  • Manolis Tsiknakis
    • 3
  • Víctor Maojo
    • 1
  1. 1.Biomedical Informatics Group, Artificial Intelligence Laboratory, School of Computer Science, Universidad Politécnica de Madrid, Campus de Montegancedo S/N, 28660 Boadilla del Monte, MadridSpain
  2. 2.Phillips Research, Healthcare System Architecture, High Tech Campus 37, 5656 AE EindhovenThe Netherlands
  3. 3.Center of eHealth Technologies, Institute of Computer Science, Foundation for Research and Technology - Hellas, GR-71110 Heraklion, CreteGreece

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