Micro and Nano Patterning for Cell and Tissue Engineering
One of the goals of bioengineers today is to answer the basic question of how individual cells, which together comprise an entire living being, communicate and interact with one another and the physical and chemical environment in which they reside. In this chapter, we will focus on the micro and nano technologies that have been used to investigate the regulation of cell functions by micro and nano features in matrix distribution, surface topography and three-dimensional (3D) microenvironment, and explore the technologies that can be applied to the fabrication of functional tissue constructs.
KeywordsTissue Engineer Neurite Extension Matrix Patterning Microcontact Printing Polymer Mold
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- 3.Li Jeon N, Baskaran H, Dertinger SK, Whitesides GM, Van de Water L, Toner M (2002) Nat Biotechnol 20:826–830Google Scholar
- 7.Li S, Bhatia S, Hu YL, Shiu YT, Li YS, Usami S, Chien S (2001) Biorheology 38:101–108Google Scholar
- 10.Clark P, Britland S, Connolly P (1993) J Cell Sci 105(1):203–212Google Scholar
- 16.Curtis A, Wilkinson C (1999) Biochem Soc Symp 65:15–26Google Scholar