Value of Digital Image Analysis in Research and Diagnosis of Urine Bladder Cancer
In this paper two methods of detecting neoplastic changes in urinary bladder are proposed: a noninvasive method mainly for screening investigations based on image analysis of specimens obtained from urine and quick little invasive method to be used as a support for clinical diagnosis based on material obtained by bladder washing technique. All together 147 cases were analyzed with the help of digital image processing system designed by the authors. Multistage classifiers were constructed to identify positive and negative cases. The results of this study yielded a 71% correct classification rate in the control group, while a 100% rate was obtained among the cancer patients for the noninvasive method. The positive test predictive value was equal to 0,77 and negative test predictive value was equal to 1. For the quick (little invasive method) the results were: a 68% correct classification rate in the control group, while a 86% rate was obtained among the cancer patients. The positive test predictive value was equal to 0,82 and negative test predictive value was equal to 0,73. The results show that both methods could be very promising additional diagnostic tools in detection of urinary bladder cancer.
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