Cancer and Pregnancy pp 39-44 | Cite as
Breast Cancer During Pregnancy: Epidemiology, Surgical Treatment, and Staging
Abstract
Historically, pregnancy-associated breast cancer was defined as breast cancer diagnosed during pregnancy and within 1 year of delivery. The present chapter deals with the situation of coincident breast cancer and pregnancy, which represents the real challenge for physicians. In fact, breast cancer diagnosed during lactation does not pose specific therapeutic problems compared to all other breast cancer and therefore is not discussed here. Moreover, the term “pregnancy-associated” somehow implies that cancer might be induced or stimulated by the presence of pregnancy, while it seems more a coincidence rather than an association. From this standpoint, we think that it might be more appropriate to define this clinical scenario simply as breast cancer during pregnancy (BCdP).
Keywords
Breast Cancer Sentinel Lymph Node Biopsy Radiat Oncol Biol Phys Pregnant Patient Breast Magnetic Resonance ImagingPreview
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References
- 1.Berry DL, Theriault RL, Holmes FA et al. (1999) Management of breast cancer during pregnancy using a standardized protocol. J Clin Oncol 17: 855–861PubMedGoogle Scholar
- 2.Bonnier P, Romain S, Dilhuydy JM, Bonichon F, Julien JP, Charpin C, Lejeune C, Martin PM, Piana L (1997) Influence of pregnancy on the outcome of breast cancer: a case-control study. Societe Francaise de Senologie et de Pathologie Mammaire Study Group. Int J Cancer 72(5): 720–727PubMedCrossRefGoogle Scholar
- 3.Cardonick E, Iacubucci A (2004) Use of chemotherapy during pregnancy. Lancet Oncol 5: 283–291PubMedCrossRefGoogle Scholar
- 4.Duncan PG, Pope WDB, Cohen MM et al. (1986) Fetal risk of anesthesia and surgery during pregnancy. Anesthesiology 64: 790–794PubMedCrossRefGoogle Scholar
- 5.Garel C, Brisse H, Sebag G et al. (1998) Magnetic resonance imaging of the foetus. Pediatr Radiol 28: 201–211PubMedCrossRefGoogle Scholar
- 6.Gentilini O, Cremonesi M, Trifirò G et al. (2004) Safety of sentinel node biopsy in pregnant patients with breast cancer. Ann Oncol 15: 1348–1351PubMedCrossRefGoogle Scholar
- 7.Gentilini O, Masullo M, Rotmensz N et al. (2005) Breast cancer diagnosed during pregnancy and lactation: biological features and treatment options. EJSO 31: 232–236PubMedCrossRefGoogle Scholar
- 8.Halakivi-Clarke L, Cho E, Onojafe I, Liao DJ, Clarke R (2000) Maternal exposure to tamoxifen during pregnancy increases carcinogen-induced mammary tumorigenesis among female rat offspring. Clin Cancer Res 6: 305–308.PubMedGoogle Scholar
- 9.Hershman DL, Wang X, McBride R, Jacobson JS, Grann VR, Neugut AI (2006) Delay in initiating adjuvant radiotherapy following breast conservation and its impact on survival. Int J Radiat Oncol Biol Phys 65(5): 1353–1360PubMedCrossRefGoogle Scholar
- 10.International Commission on Radiological Protection (2003) Biological effects after prenatal irradiation (embryo and foetus). ICRP publication 90. Ann ICRP 33(1–2): 5–206Google Scholar
- 11.Ishida T, Yokoe T, Kasumi F, Sakamoto G, Makita M, Tominaga T, Simozuma K, Enomoto K, Fujiwara K, Nanasawa T et al. (1992) Clinicopathologic characteristics and prognosis of breast cancer patients associated with pregnancy and lactation: analysis of case-control study in Japan. Jpn J Cancer Res 83(11): 1143–1149PubMedGoogle Scholar
- 12.Johansson O, Loman N, Borg A et al. (1998) Pregnancy-associated breast cancer in BRCA1 and BRCA2 germ-line mutation carriers. Lancet 352: 1359–1360CrossRefGoogle Scholar
- 13.Kal HB, Struikmans H (2005) Radiotherapy during pregnancy: fact and fiction. Lancet Oncol6: 328–333Google Scholar
- 14.Keleher A, Wendt III R, Delpassand E, Stachowiak AM, Kuerer HM (2004) The safety of lymphatic mapping in pregnant breast cancer patients using Tc-99m sulfur colloid. Breast J 10: 492–495PubMedCrossRefGoogle Scholar
- 15.Kuerer H, Gwyn K, Ames F et al. (2002) Conservative surgery and chemotherapy for breast carcinoma during pregnancy. Surgery 131: 108–110PubMedCrossRefGoogle Scholar
- 16.Lyman GH, Giuliano AE, Somerfield MR et al. (2005) American Society of Clinical Oncology Guideline Recommendations for Sentinel Lymph Node Biopsy in Early-Stage Breast Cancer J Clin Oncol 23: 7703–7720Google Scholar
- 17.Middleton LP, Amin M, Gwyn K, Theriault R, Sahin A (2003) Breast carcinoma in pregnant women: assessment of clinicopathologic and immunohistochemical features. Cancer 98(5): 1055–1060PubMedCrossRefGoogle Scholar
- 18.Mitre B, Kaubour A, Mauser N (1997) Fine needle aspiration biopsy of breast carcinoma in pregnancy and lactation. Acta Cytol 41: 1121–1130PubMedGoogle Scholar
- 19.Moore HCF, Foster RS (2000) Breast cancer and pregnancy. Semin Oncol 27: 646–653PubMedGoogle Scholar
- 20.Nicklas A, Baker M (2000) Imaging strategies in pregnant cancer patients. Semin Oncol;27: 623–632Google Scholar
- 21.Pavlidis NA, Pentheroudakis G (2005) The pregnant mother with breast cancer: diagnostic and therapeutic management. Cancer Treat Rev 31(6): 439–447PubMedCrossRefGoogle Scholar
- 22.Pentheroudakis G, Pavlidis N (2006) Cancer and pregnancy: poena magna, not anymore. Eur J Cancer 42: 126–140PubMedCrossRefGoogle Scholar
- 23.Schwartz GF, Giuliano AE, Veronesi U (2002) Consensus Conference Committee. Proceedings of the consensus conference on the role of sentinel lymph node biopsy in carcinoma of the breast, April 19–22, 2001, Philadelphia, Pennsylvania. Cancer 94(10): 2542–2551PubMedCrossRefGoogle Scholar
- 24.Schwartz GF, Veronesi U, Clough K et al. (2006) Proceedings of the Consensus Conference on Breast Conservation, April 28 to May 1, 2005, Milan, Italy Cancer 107(2): 242–250Google Scholar
- 25.Shannon J, Douglas-Jones AG, Dallimore NS (2001) Conversion to core-biopsy in preoperative diagnosis of breast lesions: is it justified by results? J Clin Pathol 54: 762–765PubMedGoogle Scholar
- 26.Vujovic O, Cherian A, Dar AR, Stitt L, Perera F (2006) Eleven-year follow up results in the delay of breast irradiation after conservative surgery in node-negative breast cancer patients. Int J Radiat Oncol Biol Phys 64(3): 760–764PubMedCrossRefGoogle Scholar
- 27.Woo JC, Yu T, Hurd TC (2003) Breast cancer in pregnancy: a literature review. Arch Surg 138: 91–99PubMedCrossRefGoogle Scholar