Management of Breast Diseases

pp 1-36

Anatomy and Physiology of the Breast

  • Martha C. JohnsonAffiliated withUniformed Services University of the Health Sciences

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This chapter is a review of the development, structure and function of the normal human breast. It is meant to serve as a backdrop and reference for the chapters that follow on pathologies and treatment. It presents an overview of normal gross anatomy, histology, and hormonal regulation of the breast followed by a discussion of its structural and functional changes from embryonic development through postmenopausal involution. This section includes recent data on some of the hormones, receptors, growth factors, transcription factors and genes that regulate this amazing nutritive organ.