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Economic Impact of Acute Kidney Failure

  • Joseph F. DastaEmail author
  • Sandra L. Kane-Gill
Chapter

Abstract

Determining the cost of an acute disease is complex. Intensive care unit (ICU) stay is a major driver of costs, and averages US $3,500 per day. Studies evaluating the costs of acute kidney injury (AKI) used widely different methods. Different AKI definitions and patient populations were some of the most notable differences in methods between studies. AKI patients generate costs that can be twofold to threefold higher than matched ICU patients not developing AKI. Renal replacement therapy and ICU length of stay are important drivers of costs of AKI patients. Patients with even small increases in serum creatinine have higher hospital and ICU costs compared with patients with no increases in serum creatinine. Therapies that prevent and/or effectively treat AKI can have substantial effects on hospital costs.

Keywords

Intensive Care Unit Renal Replacement Therapy Acute Kidney Injury Continuous Renal Replacement Therapy Intensive Care Unit Length 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Barry MC, Merriman B, Wiley M, et al. (1997) Ruptured abdominal aortic aneurysm-can treatment costs and outcomes be predicted by using clinical or physiological parameters? Eur J Vasc Endovasc Surg 14:487–491CrossRefPubMedGoogle Scholar
  2. 2.
    Bellomo R, Ronco C, Kellum JA, et al. (2004) Acute renal failure-definition, outcome measures, animal models, fluid therapy and information technology needs: the second international consensus conference of the acute dialysis quality initiative (ADQI) group. Crit Care 8: R204-R212CrossRefPubMedGoogle Scholar
  3. 3.
    Brandt M-M, Falvo AJ, Rubinfield IS, et al. (2007) Renal dysfunction in trauma: even a little less costs a lot. J Trauma 62:1362–1364CrossRefPubMedGoogle Scholar
  4. 4.
    Chertow GM, Burdick E, Honour M, et al. (2005) Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol 16:3365–3370CrossRefPubMedGoogle Scholar
  5. 5.
    Dasta JF, Kane-Gill S, Durtschi, AJ, Pathak D, Kellum J (2008) Costs and outcomes of acute kidney injury following cardiac surgery. Nephrol Dial Transplant 23:1970–4Google Scholar
  6. 6.
    Dasta JF, Durtschi AJ, Kane-Gill SL. Pharmacoeconomics, in critical care. In: Fink MP, Abraham E, Vincent J-L, Kochanek PM (eds) (2005) Textbook of Critical Care. Elsevier, Philadelphia, PAGoogle Scholar
  7. 7.
    Dasta J, Kim SR, McLaughlin TP, et al. (2005) Incremental daily cost of mechanical ventilation in patients receiving treatment in an intensive care unit. Crit Care Med 33:1266–71CrossRefPubMedGoogle Scholar
  8. 8.
    Fischer MJ, Brimhall, BB, Lezotte DC, et al. (2005) Uncomplicated acute renal failure and hospital resource utilization: a retrospective multicenter analysis. Am J Kid Dis 46:1049–1057CrossRefPubMedGoogle Scholar
  9. 9.
    Hamel MB, Phillips RS, Davis RB, et al. (1997) Outcomes and cost-effectiveness of initiating dialysis and continuing aggressive care in seriously ill hospitalized patients. Ann Intern Med 127:195–202PubMedGoogle Scholar
  10. 10.
    Korkeila M, Ruokonen E, Takala J (2000) Costs of care, long-term prognosis and quality of life in patients requiring renal replacement therapy during intensive care. Intensive Care Med 26:1824–1831CrossRefPubMedGoogle Scholar
  11. 11.
    Manns B, Doig CJ, Lee H, et al. (2003) Cost of acute renal failure requiring dialysis in the intensive care unit: clinical and resource implications of renal recovery. Crit Care Med 31:449–455CrossRefPubMedGoogle Scholar
  12. 12.
    Weber RJ, Kane SL, Oriolo V, et al. (2003) Impact of intensive care unit drug use on hospital costs: a descriptive analysis, with recommendations for optimizing ICU pharmacotherapy. Crit Care Med 31 (Suppl.):S17–S24CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  1. 1.The Ohio State University, College of Pharmacy, University of Texas, College of PharmacyHuttoUSA

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