Vitiligo pp 182-203 | Cite as

In Vivo Data

Non-Invasive Methods for Vitiligo Evaluation
Electron Microscopy

Core Messages

  • The extension and severity of vitiligo guide prognosis and help making therapeutic choices. However, in spite of attempts to standardise clinical judgment, wide variations exist both in assessment rules and interpretation of their use, making intra- and inter-observer variations unavoidable.

  • Ultraviolet (UV)-light examination and UV photography remain useful tools for the assessment of Caucasoid patients. Non-invasive instruments that use reflectance spectroscopy provide a convenient and reproducible methodology for the study of vitiligo patients and their follow-up.

  • Reflectance confocal microscopy provides microscopical informations in vivo about changes in achromic macules both in repig-mented areas after treatments and in clinically normal-appearing skin of vitiligo patients.

Keywords

Melanin Granule Vitiligo Patient Reflectance Confocal Microscopy Reflectance Spectrophotometry Epidermal Melanin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  1. 1.San Gallicano Dermatological Institutee IRCCSRomeItaly
  2. 2.Service de DermatologieHôpital Saint-André.CHU de BordeauxFrance

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