Chapter

Literature-based Discovery

Volume 15 of the series Information Science and Knowledge Management pp 75-100

Analyzing LBD Methods using a General Framework

  • A. K. SehgalAffiliated withDepartment of Computer Science, The University of Iowa
  • , X. Y. QiuAffiliated withDepartment of Management Sciences, The University of Iowa
  • , P. SrinivasanAffiliated withDepartment of Computer Science, The University of IowaDepartment of Management Sciences, The University of IowaSchool of Library and Information Science, The University of Iowa

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Abstract

This chapter provides a birds-eye view of the methods used for literature-based discovery (LBD). We study these methods with the help of a simple framework that emphasizes objects, links, inference methods, and additional knowledge sources. We consider methods from a domain independent perspective. Specifically, we review LBD research on postulating gene —disease connections, LBD systems designed for general purpose biomedical discovery goals, as well as LBD research applied to the web. Opportunities for new methods, gaps in our knowledge, and critical differences between methods are recognized when the “literature on LBD” is viewed through the scope of our framework. The main contributions of this chapter are in presenting open problems in LBD and outlining avenues for further research.