fMRI pp 127-139 | Cite as

Imaging Epileptic Seizures Using fMRI

Chapter

Abstract

Magnetic resonance imaging (MRI) has had an extraordinary impact on the diagnosis and management of epilepsy. Contemporary high-field strength MRI enables detailed in vivo imaging of lesions that underlie symptomatic epilepsies, for example, hippocampal sclerosis or malformations of cortical development. This routine use of high-field MRI in clinical epilepsy has also contributed to the increasing interest in the potential use of functional MRI (fMRI) to image the abnormal brain function that underlies epilepsy. Here, we give a brief overview of epilepsy, the current state of fMRI for the difficult problem of imaging epileptic seizures, and introduce the topic of neurovascular coupling in the epileptic brain and the constraints this imposes on fMRI interpretation.

Keywords

Status Epilepticus Arterial Spin Label Bold Signal Focal Seizure fMRI Experiment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  1. 1.The Mahoney Institute of Neurological SciencesUniversity of PennsylvaniaPhiladelphiaUSA

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