Liver

  • Laura Crocetti
  • Elena Bozzi
  • Clotilde Della Pina
  • Riccardo Lencioni
  • C. Bartolozzi
Chapter
Part of the Medical Radiology book series (MEDRAD)

Abstract

Image processing is a very important tool in improving the quantity and quality of information given by ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI) of the liver. The liver is the largest organ in the body, has a very complex anatomy and can be affected by many different diseases, including diffuse and focal diseases. Among diffuse diseases, cirrhosis has the highest prevalence and can be associated with portal hypertension and hepatocellular carcinoma (HCC) (Bartolozzi and Lencioni 1999). Cirrhotic patients are even more often candidates for orthotopic liver transplantation (OLT), and need an accurate evaluation of the liver itself and of its vascularization. Post-processing with three-dimensional (3D) evaluation of surfaces, volumes and vessels is of crucial importance in surgical planning.

Keywords

Hepatic Artery Compute Tomography Angiography Hepatic Vein Middle Hepatic Vein Maximum Intensity Projection Image 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

  1. Almusa O, Federle MP (2006) Abdominal imaging and intervention in liver transplantation. Liver Transpl. 12:184–193PubMedCrossRefGoogle Scholar
  2. Barkhausen J, Ruehm S, Goyen M et al (2001) MR evaluation of ventricular function: true fast imaging with steadystate precession versus fast low-angle shot cine MR imaging. Feasibility study. Radiology 219:264–269Google Scholar
  3. Bartolozzi C, Lencioni R (1999) Liver malignancies. Springer, BerlinGoogle Scholar
  4. Bennett WF, Bova JG, Petty L, Martin EW Jr (1991) Preoperative 3D rendering of MR imaging in liver metastases. JCAT 15:979–984Google Scholar
  5. Bismuth H, Castaing D, Garden OJ (1988) Segmental surgery of the liver. Surg Ann 20:291–310Google Scholar
  6. Bjerner T, Johansson L, Haglund U, Ahlstrom H (1998) 3D surface rendering of images from multiple MR pulse sequences in the pre-operative evaluation of hepatic lesions. Acta Radiol 39:698–700PubMedCrossRefGoogle Scholar
  7. Blasbalg R, Mitchell DG, Outwater EK, Ito K, Gabata T, Chiowanich P (2000) Free MRA of the abdomen: postprocessing dynamic gadolinium-enhanced 3D axial images. Abdom Imaging 25:62–66PubMedCrossRefGoogle Scholar
  8. Boeve WJ, Kok T, Haagsma EB et al (2001) Superior diagnostic strength of combined contrast-enhanced MR angiography and MR imaging compared to intra-arterial DSA in liver transplant candidates. Magn Reson Imaging 19:609–622PubMedCrossRefGoogle Scholar
  9. Bricault I, Kikinis R, Morrison PR et al (2006) Liver metastases: 3D shape-based analysis of CT scans for detection of local recurrence after radiofrequency ablation. Radiology 241:243–250PubMedCrossRefGoogle Scholar
  10. Byun JH, Kim TK, Lee SS et al (2003) Evaluation of the hepatic artery in potential donors for living donor liver transplantation by computed tomography angiography using multidetector-row computed tomography: comparison of volume rendering and maximum intensity projection techniques. J Comput Assist Tomogr 27:125–131PubMedCrossRefGoogle Scholar
  11. Carr JC, Nemcek AA Jr, Abecassis M et al (2003) Preoperative evaluation of the entire hepatic vasculature in living liver donors with use of contrast-enhanced MR angiography and true fast imaging with steady-state precession. J Vasc Interv Radiol 14:441–449PubMedGoogle Scholar
  12. Chaib E, Ribeiro MAF Jr, Saad WA, Gama-Rodrigues J (2005) The main hepatic anatomic variations for the purpose of split-liver transplantation. Transplant Proc 37:1063–1066PubMedCrossRefGoogle Scholar
  13. Campani R, Bottinelli O, Calliada F, Coscia D (1998) The latest in ultrasound: three dimensional imaging. Part II. Eur J Radiol 27:S183–S187CrossRefGoogle Scholar
  14. Castillo OA, Keriakos K, Stinchon JF, Jara H, Soto JA (2005) Automated liver segmentation and volume calculation from MDCT data sets using a dual-clustering technique: comparison with planimetry. Radiology (p) 509 abstractGoogle Scholar
  15. Cesarani F, Isolato G, Capello S, Bianchi SD (1999) Tridimensional ultrasonography. First clinical experience with dedicated devices and review of the literature. Radiol Med 97:256–264PubMedGoogle Scholar
  16. Coskun M, Kayahan EM, Ozbek O, Cakir B, Dalgic A, Haberal M (2005) Imaging of hepatic arterial anatomy for depicting vascular variations in living related liver transplant donor candidates with multidetector computed tomography: comparison with conventional angiography. Transplant Proc 37:1070–1073PubMedCrossRefGoogle Scholar
  17. Couinaud C (1957) Le foie: etudes anatomiques et chirurgicales. Masson, ParisGoogle Scholar
  18. Couinaud C (1986) Anatomie chirurgicale du foie: quelques aspects nouveaux. Chirurgie 112:337–342PubMedGoogle Scholar
  19. Couinaud C (1998) The dorsal sector of the liver. Chirurgie 123:8–15PubMedCrossRefGoogle Scholar
  20. Crocetti L, Della Pina C, Rocchi E, Montagnani S, Lera J, Bartolozzi C (2005) Imaging landarks for segmental lesion localization. In: Lencioni R, Cioni D, Bartolozzi C (eds.) Focal liver lesions. Springer, Berlin, pp 63–72CrossRefGoogle Scholar
  21. Downey DB, Chin JL, Fenster A (1995) Three-dimensional US-guided cryosurgery. Radiology 197(P):539Google Scholar
  22. Downey DB, Fenster A, Williams JC (2000) Clinical utility of three-dimensional US. RadioGraphics 20:559–571PubMedGoogle Scholar
  23. Ducerf C, Rode A, De La Roche E et al (1998) Compression of the celiac trunk by the diaphragmatic arcuate ligament during supramesocolonic surgery. Ann Chir 52:495–502PubMedGoogle Scholar
  24. Erbay N, Raptopoulos V, Pomfret EA, Kamel IR, Kruskal JB (2003) Living donor liver transplantation in adults: vascular variants important in surgical planning for donors and recipients. AJR Am J Roentgenol 181:109–114PubMedGoogle Scholar
  25. Friedman AC, Dachman AH (1994) Radiology of the liver, biliary tract, and pancreas. Mosby, St. LouisGoogle Scholar
  26. Fulcher A, Szucs R, Bassignani M et al (2001) Right lobe living donor liver transplantation: preoperative evaluation of the donor with MR imaging. AJR Am J Roentgenol 176:1483–1491PubMedGoogle Scholar
  27. Gilja OH, Hausken T, Bersted A, Odegaard S (1999) Measurements of organ volume by ultrasonography. Proc Inst Mech Eng 213:247–259CrossRefGoogle Scholar
  28. Glockner JF (2001) Three-dimensional gadolinium enhanced MR angiography: applications for abdominal imaging. RadioGraphics 21:357–370PubMedGoogle Scholar
  29. Glombitza G, Lamade W, Demiris AM et al (1999) Virtual planning of liver resections: image processing, visualization and volumetric evaluation. Int J Med Inf 53:225–237CrossRefGoogle Scholar
  30. Goldsmith NA, Woodburne RT (1957) The surgical anatomy pertaining to liver resection. Surg Gynecol Obstet 195:310–318Google Scholar
  31. Goodman DA, Tiruchelvan V, Tabb DR, Agarwal N, Rhoads JE Jr (1995) 3D CT reconstruction in the surgical management of hepatic injuries. Ann R Coll Surg Engl 77:7–11PubMedGoogle Scholar
  32. Guiney MJ, Kruskal JB, Sosna J, Hanto DW, Goldberg SN, Raptopoulos V (2003) Multi-detector row CT of relevant vascular anatomy of the surgical plane in split-liver transplantation. Radiology 229:401–407PubMedCrossRefGoogle Scholar
  33. Hawighorst H, Schoenberg SO, Knopp MV, Essig M, Miltner P, van Kaick G (1999) Hepatic lesions: morphologic and functional characterization with multpiphase breathhold 3D gadolinium-enhanced MR angiography-initial results. Radiology 210:89–96PubMedGoogle Scholar
  34. Healy JE (1970) Vascular anatomy of the liver. Ann NY Acad Sci 170:8–17CrossRefGoogle Scholar
  35. Healy JE, Schroy PC (1953) Anatomy of the biliary ducts within the human liver: analysis of prevailing pattern of branchings and major variations of the biliary ducts. Arch Surg 66:599–619Google Scholar
  36. Heath DG, Soyer PA, Kuszyk BS et al (1995) Three-dimensional spiral CT during arterial portography: comparison of three rendering techniques. RadioGraphics 15:1001–1011PubMedGoogle Scholar
  37. Hecht EM, Holland AE, Israel GM et al (2006) Hepatocellular carcinoma in the cirrhotic liver: gadolinium enhanced 3D T1-weighted MR imaging as a stand-alone sequence for diagnosis. Radiology 239:438–447PubMedCrossRefGoogle Scholar
  38. Henseler KP, Pozniak MA, Lee FT, Winter TC III (2001) Three-dimensional CT angiography of spontaneous portosystemic shunts. RadioGraphics 21:691–704PubMedGoogle Scholar
  39. Hiatt JR, Gabbay J, Busuttil RW (1994) Durgical anatomy of hepatic arteries in 1000 cases. Ann Surg 220:50–52PubMedCrossRefGoogle Scholar
  40. Hirai T, Ohishi H, Yamada R et al (1998) Three-dimensional power Doppler sonography of tumor vascularity. Radiat Med 16:353–357PubMedGoogle Scholar
  41. Horton KM, Fishman EK (1998) Paraumbilical vein in the cirrhotic patient: imaging with 3D CT angiography. Abdom Imaging 23:404–408PubMedCrossRefGoogle Scholar
  42. Ito K, Blasbalg R, Hussain SM, Mitchell DG (2000) Portal vein and its tributaries: evaluation with thin section three-dimensional contrast-enhanced dynamic fat-suppressed MR imaging. Radiology 215:381–386PubMedGoogle Scholar
  43. Johnson PT, Heath DG, Bliss DF, Cabral B, Fishman EK (1996a) Three dimensional CT: real-time interactive volume rendering. AJR Am J Roentgenol 167:581–583PubMedGoogle Scholar
  44. Johnson PT, Heath DG, Kuszyk BS, Fishman EK (1996b) CT angiography with volume-rendering: advantages and applications in splanchnic vascular imaging. Radiology 200:564–568PubMedGoogle Scholar
  45. Kamel IR, Kruskal JB, Pomfret EA, Keogan MT, Warmbrand G, Raptopoulos V (2001) Impact of multidetector CT on donor selection and surgical planning before living adult right lobe liver transplantation. AJR Am J Roentgenol 176:193–200PubMedGoogle Scholar
  46. Kamel IR, Liapi E, Fishman EK et al (2006) Incidental non-neoplastic hypervascular lesions in the noncirrhotic liver: diagnosis with 16-MDCT and 3D CT angiography AJR Am J Roentgenol 287:682–687CrossRefGoogle Scholar
  47. Kopka L, Rodenwaldt J, Vosshenrich R et al (1999) Hepatic blood supply: comparison of optimized dual phase contrast-enhanced three-dimensional MR angiography and digital subtraction angiography. Radiology 211:51–58PubMedGoogle Scholar
  48. Kuszyk BS, Heath DG, Ney DR et al (1995) CT angiography with volume rendering: image findings. AJR Am J Roentgenol 165:445–448PubMedGoogle Scholar
  49. Laghi A (2006) Multidetector CT (64 Slices) of the liver: examination techniques. Eur Radiol Sep 29 (Epub ahead of print)Google Scholar
  50. Lang H, Radtke A, Hindennach M et al (2005) Impact of virtual tumor resection and computer-assisted risk analysis on operation planning and intraoperative strategy in major hepatic resection. Arch Surg 140:629–638PubMedCrossRefGoogle Scholar
  51. Lavelle MT, Lee VS, Rofsky NM, Krinsky GA, Weinreb JC (2001) Dynamic contrast-enhanced three-dimensional MR imaging of liver parenchyma: souce images and angiographic reconstructions to define hepatic arterial anatomy. Radiology 218:389–394PubMedGoogle Scholar
  52. Lee SS, Kim TK, Byun JH et al (2003) Hepatic arteries in potential donors for living related liver transplantation: evaluation with multi-detector row CT angiography. Radiology 227:391–399PubMedCrossRefGoogle Scholar
  53. Lee VS, Lavelle MT, Rofsky NM et al (2000) Hepatic MR imaging with a dynamic contrast-enhanced isotropic volumetric interpolated breath-hold examination: feasibility, reproducibility, and technical quality. Radiology 215:365:372Google Scholar
  54. Lee VS, Morgan GR, Teperman LW et al (2001) MR imaging as the sole preoperative imaging modality for right hepatectomy: a prospective study of living adult-to-adult liver donor candidates. AJR Am J Roentgenol 176:1475–1482PubMedGoogle Scholar
  55. Lencioni RA, Neri E, Caramella D, Cioni D, Vagli P, Bartolozzi C (2000) Radiofrequency thermal ablation of liver malignancies: assessment of treatment outcome by volume-rendered spiral CT. Radiology 217(P):228Google Scholar
  56. Liang JD, Yang PM, Liang PC (2003) Three-dimensional power Doppler ultrasonography for demonstrating associated arteries of hepatocellular carcinoma. J Formos Med Assoc 102:367–374PubMedGoogle Scholar
  57. Linney AD, Deng J (1999) Three-dimensional morphometry in ultrasound. Proc Inst Mech Eng 213:235–245CrossRefGoogle Scholar
  58. Liess H, Roth C, Umgelter A, Zoller WG (1994) Improvements in volumetric quantificatrion of circumscribed hepatic lesions by three-dimensional sonography. Z Gastroenterol 32:488–492PubMedGoogle Scholar
  59. Makuuchi M, Hasegawa H, Yamazaki S, Takayasu K (1987) Four new hepatectomy procedures for resection of the right hepatic vein and preservation of the inferior right hepatic vein. Surg Gynecol Ostet 164:68–72Google Scholar
  60. Meier S, Schenk A, Mildenberger P, Bourquain H, Pitton M, Thelen M (2004) Evaluation of a new software tool for the automatic volume calculation of hepatic tumors. First results. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr 176:234–238PubMedCrossRefGoogle Scholar
  61. Michels N (1966) Newer anatomy of the liver and its variant blood supply and collateral circulation. Am J Surg 112:337–347PubMedCrossRefGoogle Scholar
  62. Nelson TR, Pretorius DH (1998) Three-dimensional ultrasound imaging. Ultrasound in Med & Biol 24:1243–1270CrossRefGoogle Scholar
  63. Nghiem HV, Dimas CT, Mc Vicar JP et al (1999) Impact of double helical CT and three-dimensional CT arteriography on surgical planning for hepatic transplantation. Abdom Imaging 24:278–284PubMedCrossRefGoogle Scholar
  64. Numminen K, Sipila O, Makisalo H (2005) Preoperative hepatic 3D models: virtual liver resection using three-dimensional imaging technique. Eur J Radiol 56:179–184PubMedCrossRefGoogle Scholar
  65. Okuda K, Benhamou JP (1991) Portal hypertension: clinical and physiological aspects. Springer-Verlag, TokyoGoogle Scholar
  66. Okumura A, Watanabe Y, Dohke M et al (1999) Contrast-enhanced three-dimensional MR portography. Radio-Graphics 19:973–987Google Scholar
  67. Ono N, Toyonaga A, Nishimura H, Hayabuchi N, Tanikawa K (1997) Evaluation of magnetic resonance angiography on portosystemic collaterals in cirrhotic patients. Am J Gastroenterol 92:1515–1519PubMedGoogle Scholar
  68. Park JH, Cha SH, Han JK, Han MC (1990) Intrahepatic portosystemic venous shunt. AJR Am J Roentgenol 155:527PubMedGoogle Scholar
  69. Rose SC, Hassanein TI, Easter DW et al (2001) Value of three-dimensional US for optimizing guidance for ablating focal liver tumors. J Vasc Interv Radiol 12:507–515PubMedCrossRefGoogle Scholar
  70. Saddik D, Frazer C, Robins P, Reed W, Davis S (1999) Gadolinium-enhanced three-dimensional MR portal venography. AJR Am J Roentgenol 19:973–987Google Scholar
  71. Saylisoy S, Atasoy C, Ersoz S, Karayalcin K, Akyar S (2005) Multislice CT angiography in the evaluation of hepatic vascular anatomy in potential right lobe donors. Diagn Interv Radiol 11:51–59PubMedGoogle Scholar
  72. Shinozaki K, Honda H, Yoshimitsu K et al (2002) Optimal multi-phase three-dimensional fast imaging with steadystate free precession dynamic MRI and its clinical application to the diagnosis of hepatocellular carcinoma. Radiat Med. 20:111–119PubMedGoogle Scholar
  73. Schroeder T, Radtke A, Kuehl H, Debatin JF, Malago M, Ruehm SG (2006) Evaluation of living liver donors with an all-inclusive 3D multi-detector row CT protocol. Radiology 238:900–910PubMedCrossRefGoogle Scholar
  74. Smith PA, Klein AS, Heath DG, Chavin K, Fishman EK (1998) Dual-phase spiral CT angiography with volumetric 3D rendering for preoperative liver transplant evaluation: preliminary observations. JCAT 22:868–874Google Scholar
  75. Soyer P, Roche A, Gad M et al (1991) Preoperative segmental localization of hepatic metastases: utility of three-dimensional CT during arterial portography. Radiology 180:653–658PubMedGoogle Scholar
  76. Soyer P, de Givry SC Gueye C, Lenormand S, Somveille E, Scherre A (1996a) Detection of focal hepatic lesions with MR imaging: prospective comparison of T2-weighted fast spin-echo with and without fat suppression, T2-weighted breath-hold fast spin-echo, and gadolinium chelate enhanced 3D gradient-recalled imaging. AJR Am J Roentgenol 166:1115–1121PubMedGoogle Scholar
  77. Soyer P, Dufresne AC, Somveille E, Scherrer A (1996b) Focal nodular hyperplasia of the liver: assessment of hemodynamic and angioarchitectural patterns with gadolinium chelate-enhanced 3D spoiled gradient-recalled MRI and maximum intensity projection reformatted images. JCAT 20:898–904Google Scholar
  78. Soyer P, Heath D, Bluemke DA et al (1996c) Three-dimensional helical CT of intrahepatic venous structures: comparison of three rendering techniques. JCAT 20:122–127Google Scholar
  79. Soyer P, Dufresne AC, Somveille E, Scherrer A (1997) MR imaging of the liver: effect of portal hypertension on hepatic parenchymal enhancement using a gadolinium chelate. JMRI 7:142–146PubMedCrossRefGoogle Scholar
  80. State A, Livengston MA, Garrett WF et al (1996) Technologies for augmented reality systems: realizing ultrasound-guided needle biopsies. Proceedings of SIGGRAPH’ 96. Comput Graph 13:439–446Google Scholar
  81. Taupitz M, Speidel A, Hamm B et al (1995) T2-weighted breath-hold MR imaging of the liver at 1.5 T: results with a three-dimensional steady-state free precession sequence in 87 patients. Radiology 194:439–446PubMedGoogle Scholar
  82. Togo S, Shimada H, Kanemura E et al (1998) Usefulness of three-dimensional computed tomography for anatomic liver resection: sub-subsegmentectomy. Surgery 123:73–78PubMedGoogle Scholar
  83. Uchida M, Ishibashi M, Abe T, Nishimura H, Hayabuchi N (1999) Three-dimensional imaging of liver tumors using helical CT during intravenous injection of contrast medium. JCAT 23:435–440Google Scholar
  84. van Leeuwen MS, Fernandez MA, van Es HW, Stokking R, Dillon EH, Feldberg MAM (1994a) Variations in venous and segmental anatomy of the liver: two-and three-dimensional MR imaging in healthy volunteers. AJR Am J Roentgenol 162:1337–1345PubMedGoogle Scholar
  85. van Leeuwen MS, Noordzij J, Fernandez MA, Hennipman A, Feldberg MAM, Dillon EH (1994b) Portal venous and segmental anatomy of the right hemiliver: observations based on three-dimensional spiral CT renderings. AJR Am J Roentgenol 163:1395–1404PubMedGoogle Scholar
  86. van Leween MS, Noordzij J, Hennipman A, Feldberg MA (1995) Planning for liver surgery using three dimensional imaging techniques. Eur J Cancer 31:1212–1215CrossRefGoogle Scholar
  87. Wigmore SJ, Redhead DN, Yan XJ et al (2001) Virtual hepatic resection using three-dimensional reconstruction of helical computed tomography angioportograms. Ann Surg 233:221–226PubMedCrossRefGoogle Scholar
  88. Winter TC Jr, Freeny PC, Nghiem HV et al (1995) Hepatic arterial anatomy in transplantation candidates: evaluation with three-dimensional CT arteriography. Radiology 195:363–370PubMedGoogle Scholar
  89. Wolf GK, Lang H, Prokop M, Schreiber M, Zoller W (1998) Volume measurements of localized hepatic lesions using three-dimensional sonography in comparison with three-dimensional computed tomography. Eur J Med Res 23:157–164Google Scholar
  90. Yamashita Y, Mitsuzaki K, Miyazaki T et al (1996) Gadolinium-enhanced breath-hold three-dimensional MR angiography of the portal vein: value of the magnetization-prepared rapid acquisition gradient-echo sequence. Radiology 201: 283–288PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2008

Authors and Affiliations

  • Laura Crocetti
    • 1
  • Elena Bozzi
    • 1
  • Clotilde Della Pina
    • 1
  • Riccardo Lencioni
    • 1
  • C. Bartolozzi
    • 1
  1. 1.Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants and New Technologies in MedicineUniversity of PisaPisaItaly

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