Tryptophan dimethylallyltransferase

Part of the Springer Handbook of Enzymes book series (HDBKENZYMES, volume 34)

Nomenclature

EC number

2.5.1.34

Systematic name

dimethylallyl-diphosphate:l-tryptophan dimethylallyltransferase

Recommended name

tryptophan dimethylallyltransferase

Synonyms

4-(γ,γ-dimethylallyl)tryptophan synthase

DMAT synthase

DMAT synthetase

dimethylallylpyrophosphate:l-tryptophan dimethylallyltransferase

dimethylallylpyrophosphate:tryptophan dimethylallyl transferase

dimethylallylpyrophosphate:tryptophan dimethylallyltransferase

dimethylallyltransferase, tryptophan

dimethylallyltryptophan synthetase

CAS registry number

55127-01-0

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References

  1. [1]
    Lee, S.L.; Floss, H.G.; Heinstein, P.: Purification and properties of dimethylallylpyrophosphate:tryptopharm dimethylallyl transferase, the first enzyme of ergot alkaloid biosynthesis in Claviceps. sp. SD 58. Arch. Biochem. Biophys., 177, 84–94 (1976)PubMedCrossRefGoogle Scholar
  2. [2]
    Shibuya, M.; Chou, H.M.; Fountoulakis, M.; Hassam, S.; Kim, S.-U.; Kobayashi, K.; Otsuka, H.; Rogalska, E.; Cassady, J.M.; Floss, H.G.: Stereochemistry of the isoprenylation of tryptophan catalyzed by 4-(γ,γ-dimethylallyl)tryptophan synthase from Claviceps, the first pathway-specific enzyme in ergot alkaloid biosynthesis. J. Am. Chem. Soc, 112, 297–304 (1990)CrossRefGoogle Scholar
  3. [3]
    Rilling, H.C.: Dimethylallylpyrophosphate: l-tryptophan dimethylallyltransferase. Methods Enzymol., 110, 335–340 (1985)PubMedCrossRefGoogle Scholar
  4. [4]
    Gebler, J.C.; Poulter, C.D.: Purification and characterization of dimethylallyl tryptophan synthase from Claviceps purpurea. Arch. Biochem. Biophys., 296, 308–313 (1992)PubMedCrossRefGoogle Scholar
  5. [5]
    Cress, W.A.; Chayet, L.T.; Rilling, H.C.: Crystallization and partial characterization of dimethylallyl pyrophosphate: l-tryptophan dimethylallyltransferase from Claviceps sp. SD58. J. Biol. Chem., 256, 10917–10923 (1981)PubMedGoogle Scholar
  6. [6]
    Tsai, H.-R; Wang, H.; Gebler, J.C.; Poulter, C.D.; Schardl, C.L.: The Claviceps purpurea gene encoding dimethylallyltryptophan synthase, the committed step for ergot alkaloid biosynthesis. Biochem. Biophys. Res. Commun., 216, 119–125 (1995)PubMedCrossRefGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 2007

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