Biological Applications of Microtomography

  • J. C. Elliott
  • R. Boakes
  • S. D. Dover
  • D. K. Bowen
Part of the Springer Series in Optical Sciences book series (SSOS, volume 56)

Abstract

X-ray microtomography can be used to obtain, non-destructively, 3-dimensional information about biological structures at a resolution of a few microns. The information may be purely morphological, but if accurately monochromatic X-radiation is used, the results are in the form of the 3-dimensional distribution of the linear absorption coefficient.

The X-ray source used was a microfocus X-ray generator with a 100 pm source and molybdenum target. The transmitted X-ray intensity of the sample was measured with a high purity germanium detector which allows the measurements to be made with monochromatic radiation.This system was used to determine the quantitative distribution of X-ray absorption in a rat rib bone and elephant dentine (ivory).

Keywords

Linear Absorption Coefficient Molybdenum Target Mineral Density Distribution Electron Microscopy Serial Section London Hospital Medical College 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    J.C. Elliott, S.D. Dover: Metab. Bone Dis. Rel. Res. 5, 219 (1984)CrossRefGoogle Scholar
  2. 2.
    J.C. Elliott, S.D. Dover: J. Microscopy 138, 329 (1985)CrossRefGoogle Scholar
  3. 3.
    D.K. Bowen, J.C. Elliott, S.R. Stock, S.D. Dover: In X-ray Imaging II, SPIE Vol. 691 p. 94 (1986)CrossRefGoogle Scholar
  4. 4.
    A. Yu. Sasov: J. Microscopy 147, 169 (1987)CrossRefGoogle Scholar
  5. 5.
    A. Yu. Sasov: J. Microscopy, 147, 179 (1987)CrossRefGoogle Scholar
  6. 6.
    B.P. Flannery, H.W. Deckman, W.G. Roberge, K.L. D’Amico: Science 237, 1439 (1987)ADSCrossRefGoogle Scholar
  7. 7.
    J.C. Elliott, D.K. Bowen, S.D. Dover, S.T. Davies: Biol. Trace Elem. Res. 13, (in press)Google Scholar
  8. 8.
    S.D. Dover, J.C. Elliott, R. Boakes, D.K. Bowen: J. Microscopy (in press)Google Scholar
  9. 9.
    J.E. Hamos, S.C. van Horn, D. Raczkowski, S.M. Sherman: J. Comp. Neurology 259, 165 (1987)CrossRefGoogle Scholar
  10. 10.
    M.D. Grynpas, P. Patterson-Allen, D.J. Simmons: Calcif. Tissue Int. 39, 57 (1986)CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • J. C. Elliott
    • 1
  • R. Boakes
    • 1
  • S. D. Dover
    • 2
  • D. K. Bowen
    • 3
  1. 1.Dept of BiochemistryThe London Hospital Medical CollegeLondonUK
  2. 2.Dept of BiophysicsKing’s CollegeLondonUK
  3. 3.Dept of EngineeringUniversity of WarwickCoventryUK

Personalised recommendations