Physiology of Penile Erection and Pathophysiology of Erectile Dysfunction
Penile erection is primarily a neurovascular event modulated by psychological and hormonal status. Sexual stimulation causes a release of neurotransmitters from the cavernous nerve terminals and relaxing factors from the endothelial cells in the penis, resulting in relaxation of smooth muscle in the arteries and arterioles supplying the erectile tissue.
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