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Development of the Enteric Nervous System

  • P. Puri
  • U. Rolle

Abstract

The enteric nervous system (ENS) is the largest and the most complex division of the peripheral nervous system [1]. The ENS contains more neurons than the spinal cord and is capable of mediating reflex activity in the absence of central nervous system. About 80–100 million enteric neurons can be classified into functional distinct subpopulations, including intrinsic primary neurons, interneurons, motor neurons, secretomotor and vasomotor neurons [2]. The ENS plays a crucial role in normal gastrointestinal motility. Therefore insights into the development of the gastrointestinal tract and the ENS are relevant for the understanding of the pathophysiology and treatment of infants and children with motility disorders.

Keywords

Neural Crest Enteric Nervous System Myenteric Plexus Enteric Neuron Intestinal Neuronal Dysplasia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2008

Authors and Affiliations

  • P. Puri
    • 1
  • U. Rolle
    • 2
  1. 1.Children’s Research Centre, Our Lady’s Children’s HospitalUniversity College of DublinCrumlinIreland
  2. 2.Department of Paediatric SurgeryUniversity of LeipzigLeipzigGermany

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