Multislice CT pp 333-355 | Cite as

Interstitial Lung Diseases

  • Christina Mueller-Mang
  • Christina Plank
  • Helmut Ringl
  • Albert Dirisamer
  • Christian J. Herold
Part of the Medical Radiology book series (MEDRAD)


The term interstitial lung disease (ILD) comprises a diverse group of diseases that lead to inflammation and fibrosis of the alveoli, distal airways, and septal interstitium of the lungs. The ILDs consist of disorders of known cause (e.g., collagen vascular diseases, drug-related diseases) as well as disorders of unknown etiology. The latter include idiopathic interstitial pneumonias (IIPs), sarcoidosis and a group of miscellaneous, rare, but nonetheless interesting, diseases. In patients with ILD, MDCT enriches the diagnostic armamentarium by allowing volumetric high resolution scanning, i.e., continuous data acquisition with thin collimation and a high spatial frequency reconstruction algorithm. CT is a key method in the identification and management of patients with ILD. It not only improves the detection and characterization of parenchymal abnormalities, but also increases the accuracy of diagnosis. The spectrum of morphologic characteristics that are indicative of interstitial lung disease is relatively limited and includes a reticular pattern (with or without traction bronchiectasis), thickening of interlobular septa, honeycombing, nodules, and ground-glass opacities. In the correct clinical context, some patterns or combination of patterns, together with the anatomic distribution of the abnormality, i.e., from the lung apex to the base, or peripheral subpleural versus central bronchovascular, can lead the interpreter to a specific diagnosis. However, due to an overlap of the CT morphology between the various entities, complementary lung biopsy is recommended in virtually all cases of ILDs.


Interstitial Lung Disease Usual Interstitial Pneumonia Pulmonary Alveolar Proteinosis Idiopathic Interstitial Pneumonia Traction Bronchiectasis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2009

Authors and Affiliations

  • Christina Mueller-Mang
    • 1
  • Christina Plank
    • 1
  • Helmut Ringl
    • 1
  • Albert Dirisamer
    • 1
  • Christian J. Herold
    • 1
  1. 1.Department of Diagnostic and Pediatric RadiologyMedical University of ViennaViennaAustria

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