Tree-Dependent and Topographic Independent Component Analysis for fMRI Analysis

  • Anke Meyer-Bäse
  • Fabian J. Theis
  • Oliver Lange
  • Carlos G. Puntonet
Part of the Lecture Notes in Computer Science book series (LNCS, volume 3195)


Recently, a new paradigm in ICA emerged, that of finding “clusters” of dependent components. This striking philosophy found its implementation in two new ICA algorithms: tree–dependent and topographic ICA. Applied to fMRI, this leads to the unifying paradigm of combining two powerful exploratory data analysis methods, ICA and unsupervised clustering techniques. For the fMRI data, a comparative quantitative evaluation between the two methods, tree–dependent and topographic ICA was performed. The comparative results were evaluated based on (1) correlation and associated time–courses and (2) ROC study. It can be seen that topographic ICA outperforms all other ICA methods including tree–dependent ICA for 8 and 9 ICs. However, for 16 ICs topographic ICA is outperformed by both FastICA and tree–dependent ICA (KGV) using as an approximation of the mutual information the kernel generalized variance.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2004

Authors and Affiliations

  • Anke Meyer-Bäse
    • 1
  • Fabian J. Theis
    • 1
    • 2
  • Oliver Lange
    • 1
    • 3
  • Carlos G. Puntonet
    • 4
  1. 1.Department of Electrical and Computer EngineeringFlorida State UniversityTallahasseeUSA
  2. 2.Institute of BiophysicsUniversity of RegensburgRegensburgGermany
  3. 3.Department of Clinical RadiologyLudwig–Maximilians UniversityMunichGermany
  4. 4.Department of Architecture and Computer TechnologyUniversity of GranadaSpain

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