Modelling Spikes with Mixtures of Factor Analysers
Identifying the action potentials of individual neurons from extracellular recordings, known as spike sorting, is a challenging problem. We consider the spike sorting problem using a generative model, mixtures of factor analysers, which concurrently performs clustering and feature extraction. The most important advantage of this method is that it quantifies the certainty with which the spikes are classified. This can be used as a means for evaluating the quality of clustering and therefore spike isolation. Using this method, nearly simultaneously occurring spikes can also be modelled which is a hard task for many of the spike sorting methods. Furthermore, modelling the data with a generative model allows us to generate simulated data.
KeywordsDimensionality Reduction Gaussian Mixture Model Factor Analysis Model Manual Cluster Spike Detection
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