Non-opioid Intravenous Infusions for Management of Cancer-Associated Pain

  • Yury Khelemsky
  • Mourad M. Shehabar


Opioids have long been at the foundation of treating cancer-related pain; however, non-opioid intravenous infusions have become meaningful alternatives and adjuncts. Cancer-associated pain, which results from the disease process or as sequelae of treatment, is often challenging to control and may not respond to standard analgesic regimens. Lidocaine, ketamine, bisphosphonates, as well as various radioisotopes have been utilized as infusions to provide analgesia and decrease reliance on opioids, which have numerous unfavorable side effects.


Cancer-related pain Infusion Lidocaine Ketamine Bisphosphonate Strontium-89 Radium-223 Denosumab 


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Yury Khelemsky
    • 1
  • Mourad M. Shehabar
    • 1
  1. 1.Icahn School of Medicine at Mount Sinai, Department of AnesthesiologyNew YorkUSA

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