• Simon S. LoEmail author
  • Tithi Biswas
  • Rodney J. Ellis
  • Peter C. Gerszten


With the availability of advanced technology and radiation delivery techniques, it is now possible to deliver high doses of radiation precisely and accurately to a specific tumor volume with a very low risk of toxicity. Building upon the experience on intracranial stereotactic radiosurgery (SRS), stereotactic body radiotherapy (SBRT), also called “extracranial surgery,” has emerged as an extremely effective nonsurgical local therapy option for cancer pain control. While there is a relatively large body of data on the use of SBRT for the palliation of pain from spinal metastases, the data on the use of SBRT for palliation of pain from non-spinal bone and visceral metastases are quite limited. More research and clinical trials are needed to better define the role of “extracranial radiosurgery” for cancer pain control.


Stereotactic body radiotherapy Spinal metastasis Bone metastasis Visceral metastasis Cancer pain control 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Simon S. Lo
    • 1
    Email author
  • Tithi Biswas
    • 2
  • Rodney J. Ellis
    • 2
  • Peter C. Gerszten
    • 2
  1. 1.University of Washington School of Medicine, Department of Radiation OncologySeattleUSA
  2. 2.University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Department of Radiation OncologyClevelandUSA

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