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Targeted Therapeutic Nanoparticles for Cancer and Other Human Diseases

  • Rabiatul Basria S. M. N. MydinEmail author
  • Wan Nordiana Rahman
  • Rosmazihana Mat Lazim
  • Amirah Mohd Gazzali
  • Nur Hazirah Mohd Azlan
  • Said Moshawih
Chapter

Abstract

Targeted drug delivery is a useful approach to enhanced the present therapeutic efficacy in treating human diseases especially cancers. Nanoparticles is known for its ability to act as passive targeting agent through the enhanced permeability and retention effects and it has also shown promising results for drug or gene delivery, radiotherapy and photodynamic therapy applications. This chapter will describe the different organic and inorganic therapeutic nanoparticles that may be used with specific applications. These materials will be explained in brief alongside the reported research works and its related applications.

Keywords

Targeted therapeutic nanoparticles Solid lipid nanoparticle Tumor-specific targeting nanoparticles Nanoparticles for gene delivery Therapeutic nanosystems Superparamagnetic iron oxide nanoparticles Nanoparticles for photodynamic therapy 

Notes

Acknowledgements

The authors are thankful to the Ministry of Education (MOE) Malaysia for funding this work under Transdisciplinary Research Grant Scheme (TRGS) grant no. 6769003. The authors are very much grateful to Universiti Sains Malaysia (USM) for providing the necessary facilities to carry out the research work and financial support under USM-Short Term Research Grant (304/CIPPT/6315073).

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Authors and Affiliations

  • Rabiatul Basria S. M. N. Mydin
    • 1
    Email author
  • Wan Nordiana Rahman
    • 2
  • Rosmazihana Mat Lazim
    • 2
  • Amirah Mohd Gazzali
    • 3
  • Nur Hazirah Mohd Azlan
    • 1
  • Said Moshawih
    • 4
  1. 1.Oncological and Radiological Sciences Cluster, Advanced Medical and Dental InstituteUniversiti Sains MalaysiaKepala BatasMalaysia
  2. 2.Medical Radiation Programme, School of Health SciencesUniversiti Sains Malaysia (Health Campus)Kubang KerianMalaysia
  3. 3.School of Pharmaceutical SciencesUniversiti Sains MalaysiaMindenMalaysia
  4. 4.Jordan Center for Pharmaceutical ResearchAmmanJordan

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